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Does IVIG affect your IgG level?

by loveparis on Tue Apr 04, 2017 5:27 pm

Does anyone know if IVIG has any effect on IgG levels?

I've had 2 monthly infusions after a long bout of pneumonia. My IgG level went from 520 to 900, then most recently to 1000.

I'm 9 months post stem cell transplant. My levels were high at diagnosis, then dropped dra­mat­ically with induction and transplant. I'm concerned and am waiting for my other myeloma labs to come back soon.

Just feeling a little worried but waiting to see the rest of labs. Any thoughts welcome.

LP

loveparis
Name: loveparis
Who do you know with myeloma?: myself
When were you/they diagnosed?: June, 2015
Age at diagnosis: 61

Re: Does IVIG affect your IgG level?

by jhorner on Tue Apr 04, 2017 6:29 pm

Hello Loveparis,

Yes, IVIG does effect your IgG level. I usually have my myeloma panel on the day of IVIG and they draw the blood prior to the infusion to get a better read on my numbers. The half life of IVIG is 20 days so even still my tests are not 100% accurate as they would be if I had not been on IVIG therapy.

I had blood work done after infusion once because the original draw was hemolyzed, and my IgG was almost 3,000.

I hope this helps.
J

jhorner
Name: Magpie
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 2013
Age at diagnosis: 49

Re: Does IVIG affect your IgG level?

by Multibilly on Tue Apr 04, 2017 7:17 pm

Loveparis,

The whole idea behind IVIG treatment is to raise one's IgG level ;-) IVIG is in fact pre­domi­nantly IgG that has been collected from blood donors.

At an IgG level of 590 mg/dL, your IgG was below normal. So based on your low IgG level and having pneumonia, they started you on IVIG treatment to boost your IgG level so as to fight off the pneumonia.

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012


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