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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Is it OK to take anti-inflammatory (ibuprofen)?

by Maro on Thu Jul 09, 2015 5:44 am

Hello everyone,

My mother who has myeloma suffers from recurring sciatic nerve issues. She also has a scoliosis.
She has always suffered from back pain since over 20 years and has always taken anti-inflammatory drugs (ibuprofen mostly).

Is it OK to take these drugs while having myeloma?

We were told that it is not good for the kidneys and knowing that myeloma can affect the kidneys she has stopped taking ibuprofen for over a year to the detriment of her pain (non myeloma related).

Her kidney function is normal.

Please, what are your thoughts? Can one take ibuprofen while having myeloma without the risk of damaging the kidneys?

Thanks,

Maro

Maro
Who do you know with myeloma?: My mom
When were you/they diagnosed?: March 2014
Age at diagnosis: 63

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by Eric Hofacket on Thu Jul 09, 2015 10:01 am

I have seen a number of the Beacon medical advisors caution about taking ibuprofen because in myeloma patients the kidneys can already be stressed from effects of myeloma itself and the drugs used to treat it. Ibuprofen can add additional stress. It can be important to keep the kidneys healthy as it can limit future treatment options and many clinical trials will exclude applicants that have poor kidney health. The advice from the Beacons medical advisors has always been to discuss this and consult with the patients doctor who can examine the patients and has access to the lab results and medical case to make a decision about if ibuprofen is save or not for a patient. If it were me I would not take my guidance from someone the internet on this over my doctor.

Having said that you might have your mother take a look at curcumin to see if that may provide some relieve to her arthritis pain. If you have been reading and researching myeloma a lot you probably have come across curcumin and its potential anti-myeloma properties. I have taken curcumin myself though I am on the fence about whether curcumin has potent anti-myeloma properties or not. But I have read that curcumin is supposed to be a natural anti-inflammatory and its effects as an anti-inflammatory have been vetted. I have read accounts from other Beacon readers curcumin has helped with the inflammation problems. Maybe it could help your mother too if she is not able to take ibuprofen? As stated earlier it would be best to discuss all this with her doctor. Best wishes,
Eric

Eric Hofacket
Name: Eric H
When were you/they diagnosed?: 01 April 2011
Age at diagnosis: 44

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by mikeb on Thu Jul 09, 2015 11:24 am

Hi Maro,

I concur with what Eric said about ibuprofen. I've gotten the same advice-not to take it-from my myeloma specialist.

For minor pain, my doctor recommends Tylenol (acetaminophen, paracetamol).

Mike

mikeb
Name: mikeb
Who do you know with myeloma?: self
When were you/they diagnosed?: 2009 (MGUS at that time)
Age at diagnosis: 55

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by Bar-none on Thu Jul 09, 2015 1:46 pm

Ditto here. No NSAIDs that put any additional stress on kidney or liver per my doc.

Best! BN

Bar-none
Who do you know with myeloma?: Me
When were you/they diagnosed?: 3/14

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by Maro on Thu Jul 09, 2015 7:50 pm

Thank you all for your answers. I was mostly seeking opinions I assure you I was not going to over rule doctors advice ;-)

Maro
Who do you know with myeloma?: My mom
When were you/they diagnosed?: March 2014
Age at diagnosis: 63

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by NStewart on Fri Jul 10, 2015 8:07 am

One of the things that you might ask her oncologist for is a referral to a pain specialist. This person could work with your mother to develop a pain control strategy that would be safe for her.
Nancy in Phila

NStewart
Name: Nancy Stewart
Who do you know with myeloma?: self
When were you/they diagnosed?: 3/08
Age at diagnosis: 60

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by goldmine848 on Mon Jul 13, 2015 8:49 pm

Likewise my oncologist has counseled against ibuprofen and naproxyn. He did, however, prescribe celebrex.

goldmine848
Name: Andrew
When were you/they diagnosed?: June 2013
Age at diagnosis: 60

Re: Is it OK to take anti-inflammatory (ibuprofen)?

by smarty on Tue Jul 14, 2015 5:03 am

I don't wish to advise anyone to go against doctor's orders but are you aware Celebrex is also an NSAID? Have you looked it up and noted its side effects?

I attempted it years ago and found out it was not advisable with thyroid disease and caused stomach problems although claims less than ibuprofen. Perhaps for some myeloma patients it is o.k.

smarty
Name: Marti
Who do you know with myeloma?: myself Smoldering Myeloma
When were you/they diagnosed?: May 1, 2015
Age at diagnosis: 76


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