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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

How long between stopping treatment & stem cell harvest?

by DallasGG on Sat Dec 28, 2013 7:02 pm

I stopped treatment a little over 5 weeks ago (37 days to be exact) in anticipation of getting ready for a stem cell harvest. I went through the testing for the stem cell harvest about 2 weeks ago and am waiting for my doctor's office to contact me to schedule the harvest. Fortunately the bone marrow biopsy I had 2 weeks ago shows no multiple myeloma (down from 80% to begin with 5-6 months ago).

I'm just what the length of time usually is between the time treatment is stopped and when the stem cell harvest / stem cell collection takes place? Is there an optimal amount of time between stopping treatments and starting the harvest?

I guess I'm also interested what the usual time is between stem cell harvest and stem cell transplant, when the transplant is done soon after the stem cell collection.

DallasGG
Name: Kent
Who do you know with myeloma?: myself
When were you/they diagnosed?: 6/20/2013
Age at diagnosis: 56

Re: How long between stopping treatment & stem cell harvest

by LadyLib on Sat Dec 28, 2013 10:26 pm

Good evening.

My husband was diagnosed in July 2013. HIs last treatment (5 cycles of VCD - Velcade, cyclo­phos­phamide, and dexamethasone) was November 22. He started the collection process on December 15th. He did Neupogen shots for 4 days. They collected on Day 3 (December 18) and Day 4 (December 19). They gave him a week off for the holidays. He had pre-screen on December 26th. He is now on Day 2 of melphalan. Today is our day off. Then, transplant on Monday (Day 0).

So things have went relatively quickly. He was 50% involved at diagnosis and down to less than 2% after 5 cycles. No M-spike in the urine after treatment.

LadyLib
Name: LadyLib
Who do you know with myeloma?: Spouse
When were you/they diagnosed?: July 2013
Age at diagnosis: 42

Re: How long between stopping treatment & stem cell harvest?

by Tydahs87 on Thu Sep 07, 2017 6:54 pm

My dad is at the Cleveland Clinic harvesting stem cells for his transplant that is scheduled to happen next Wednesday. His harvest has not been successful so far.

I have found during research that almost everyone I have seen has had 4-6 weeks minimum off of Revlimid as a "wash cycle" before harvest. My father has only been off of Revlimid since the last week of August, which is a little less that 2 weeks before his harvest started. So I've been wondering if that could be the reason for the trouble he's had harvesting.

Tydahs87
Name: Ty
Who do you know with myeloma?: My Father
When were you/they diagnosed?: December 2016
Age at diagnosis: 56

Re: How long between stopping treatment & stem cell harvest?

by Pauillac on Mon Sep 11, 2017 4:32 pm

Hello,

My wife was taking thalido­mide, which apparently is very similar to Revlimid. She started the collection process 3 days after stopping thalido­mide.

Collection was done with a first Endoxan (cyclophosphamide) chemo and 10 days of Zarzio 30 growth factor (Neupogen biosimilar).

Not sure it can help, as every patient is different.

All the best.

Pauillac
Name: Louise Rose
Who do you know with myeloma?: my wife
When were you/they diagnosed?: March 2017
Age at diagnosis: 42


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