[Lacerta]

High kappa / lambda ratio before stem cell transplant

by Lacerta on Wed Apr 13, 2016 5:01 pm

Hi,

My mother will this week start with her stem cell transplant treatment. It is 6 weeks ago since she got the last treatment with Velcade.

I do not have the exact numbers at the moment of writing, but since February the serum kappa / lambda ratio has increased from about 5 to 600 mg/L. At moment of diagnosis (October 2015), the ratio was 3400 mg/L, but to about 5 in November 2015 after treatment, and being stable in December-February. Since February there was a break without measuring kappa / lambda ratio, and now just before the stem cell transplant the ratio has increased to 600 mg/L, which worries us.

Does kappa/lambda ratio vary a lot during treatment? And is this value important for the prognosis?

Thanks for help.

[MMFeb16,15]

Re: High kappa / lambda ratio before stem cell transplant

by MMFeb16,15 on Fri Apr 15, 2016 5:41 am

Dear Lacerta,

FLC readings (kappa, lambda and ratio) vary a lot during treatment. Your physician/hematologist will be the best person to answer your specific question.

I wish your mom successful ASCT.