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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

High-dose chemo and fasting

by Ellen w on Mon Aug 10, 2015 12:30 pm

Hi,

I have been following the Beacon since my husband was told he had multiple myeloma. Thank you so much for sharing, it's been a huge help.

My question is: Has anyone used fasting to help with side effects of high-dose chemo for stem cell collection and transplant?

Ellen w
Name: Ellen
Who do you know with myeloma?: Husband
When were you/they diagnosed?: January 2015
Age at diagnosis: 52

Re: High-dose chemo and fasting

by Blackbird on Mon Aug 10, 2015 1:16 pm

If you are referring to the high dose chemo you receive FOR the stem cell transplant, he will be fasting (for the most part) whether he wants to or not. I had zero appetite shortly after receiving the melphalan along with a lot of nausea. They have good medications to control the nausea, but it really didn't help my appetite.

Also, for what it's worth, they want you to eat. They won't try to force you to, but they do want you to (at least in my case).

Blackbird
Name: Rick Crow
Who do you know with myeloma?: Me
When were you/they diagnosed?: Feb, 2013
Age at diagnosis: 53

Re: High-dose chemo and fasting

by Ellen w on Mon Aug 10, 2015 4:22 pm

According to the doctor in Canada, high-dose cyclophosphamide is used before stem cell col­lection. She said it was standard. Is it normal elsewhere?

Ellen w
Name: Ellen
Who do you know with myeloma?: Husband
When were you/they diagnosed?: January 2015
Age at diagnosis: 52

Re: High-dose chemo and fasting

by Blackbird on Mon Aug 10, 2015 4:55 pm

Prior to my stem cell collection I gave myself shots of neupogen to stimulate stem cell production for the collection.

My induction chemo (prior to the stem cell collection) consisted of Velcade and dex. They added 25 mg Revlimid towards the end when my numbers started to plateau.

Nothing that I was given was consider "high dose" until I received the melphalan for the sct.

Blackbird
Name: Rick Crow
Who do you know with myeloma?: Me
When were you/they diagnosed?: Feb, 2013
Age at diagnosis: 53

Re: High-dose chemo and fasting

by Joneman on Mon Aug 10, 2015 7:07 pm

You won't have to worry about fasting after the transplant as you will be so nauseous that you won't want to eat for months. Popsicles help with the nausea.

Joneman

Re: High-dose chemo and fasting

by Ginny on Mon Aug 10, 2015 7:44 pm

I agree that the others; fasting during a stem cell transplant is basically involuntary. I wouldn't recommend fasting any more than comes naturally. It is important to eat as much as possible for at least two reasons: calories are needed to rebuild the tissues destroyed by the chemo and not eating makes you much weaker and makes recovery longer and harder. Whenever I didn't eat a meal the kitchen sent up a bottle of Ensure, a protein drink.

Ginny
Name: Ginny
Who do you know with myeloma?: self and four friends
When were you/they diagnosed?: October, 2012
Age at diagnosis: 62

Re: High-dose chemo and fasting

by Ginny on Mon Aug 10, 2015 7:46 pm

Forgot to say ... I had fairly high-dose cyclophosphamide before my cell harvesting, then high-dose melphalan before the transplant.

Good luck!

Ginny

Ginny
Name: Ginny
Who do you know with myeloma?: self and four friends
When were you/they diagnosed?: October, 2012
Age at diagnosis: 62

Re: High-dose chemo and fasting

by stinky on Mon Aug 10, 2015 8:10 pm

I had my stem cell transplant in 2010 and will be back on chemo next month. In the hospital they gave me 2 different anti-nausea drugs and they worked. When I got home, I had some pills that I hardly needed. I did find that even the angel hair pasta that I started eating had a metallic taste. It was suggested that I use plastic knives and forks. That did the trick.

In the hospital, I had almost no desire to eat, not from the nausea but from fatigue. Nausea should not be a problem in the hospital. I got one drug and about an hour later a different one, when needed, and it worked great. I was very tired from not eating and that can be a problem. I felt it important to eat when I could to keep my strength.

Best of luck and I hope this helps.

stinky

Re: High-dose chemo and fasting

by Barbarah on Mon Aug 10, 2015 10:43 pm

At Mayo Rochester after a SCT, one has a daily appointment with a nutritionist who checks a booklet in which one keeps track of food and calories consumed each day. Since I never felt like eating, I lived on root beer floats at the hospital (which taste just as they should) and strawberry milkshakes, which my husband prepared every evening. Each tasteless bite of any other food (soup, yogurt, oatmeal) had to be forced down. I now hate even the smell of Ensure. Nearly fasting, but not my choice!

In spite of the loss of appetite and taste, I was never nauseated and took no medicine to combat it. In the final analysis, I was pleased with my weight loss and maintained it for two years until the next treatment, which included dex.

Barbarah
Name: Barbarah
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 11-2008
Age at diagnosis: 66

Re: High-dose chemo and fasting

by Robert spano on Tue Aug 11, 2015 4:14 am

My wife had nausea during her transplant. We finally figured out that it was mostly caused by the anti-fungal agent. Too bad no one figured that out and gave her an alternative.

Robert spano

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