[Chubbybird]

Help to decipher

by Chubbybird on Sat Oct 05, 2013 2:21 pm

Immunochemistry, protien electrophoresis
Total protien 68.0. 60-80.0
Albumin 41.3. 40-54
Alpha-1. 1.7. 1.0-2.2
Alpha-2. 7.5. 5.0-9.2
Beta. 8.0. 5.1-13.2
Comments: pep shows presence of a homogeneous band in between beta and ganna go bullion region.

Immunoelectrophoresis-ser
Igg. Decreased
Iga. Abnormal
Igm. Normal
Comments: serum protien electrophoresis demonstrates two homogeneous bands in the beta gamma accounting for approximately 30% of the gamma fraction

Serum protien immunofixation/immunoelecrophoresis demonstrate the homogeneous bands are monoclonal IGA lambda immunoglobulin abnormality Igm is present in normal level. Total igg decreased and iga increased

Impression:monoclonal iga lambda immunoglobulin abnormality with some suppression of other immunoglobulin Compatible with multiple myeloma or other malinancy or mgus

Immunocheststry immunoquanitifcatin

Igg. 5.59. 5.64-17.65
Iga. 9.24. 0.85-3.85
Igm. 0.52. 0.45-2.50

Last test showed m protien spike. But not sure of the value

Any comment on if I should be concerned or help to understand. Would be greatly appreciated

[Multibilly]

Re: Help to decipher

by Multibilly on Sat Nov 09, 2013 8:48 am

It's really tough to make any sort of a call from just this data. I assume you must have a GP or hematologist that ordered these tests and that you would debrief with him/her? Based on your elevated IgA, there is certainly a chance you have some stage of myeloma from these tests, but it could just be an early stage of the disease like MGUS that may not go anywhere for the rest of your life. You just can't tell from only this data.

You really need to know the value of your M-Spike and have some other tests to determine if your have any any organ or bone damage.... and ultimately a bone marrow biopsy to determine what is going on with your plasma cells in your bones. See the other tests required here: http://myeloma.org/ArticlePage.action?tabId=1&menuId=322&articleId=3177&aTab=-1

There is enough data here to warrant seeing a myeloma specialist as your next step. Don't just work with a GP or general purpose oncologist when it comes to this disease. This is the most important piece of advice anybody on this forum can give you.

Best of luck.