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Gene crossovers

by Jubyanne on Fri Mar 15, 2013 4:32 pm

Where do gene irregularities occur? Are they only on the myeloma cells? Are they in all our cells? Mine is 4/14 crossover.

Jubyanne

Jubyanne
Name: Julia Munson
Who do you know with myeloma?: myself, son's mother-in-law
When were you/they diagnosed?: Spring 2008
Age at diagnosis: 65

Re: Gene crossovers

by TerryH on Fri Mar 15, 2013 4:48 pm

Hi Jubyanne,

Your question is one that I always wondered about as well.

As best I can determine, when myeloma researchers talk about finding chromosomal abnormalities like t(4;14) -- which is the one that you have -- they are talking about abnormalities occurring in the myeloma cells, not the other cells in a patient's body.

TerryH

Re: Gene crossovers

by Dr. Peter Voorhees on Mon Mar 18, 2013 12:25 am

TerryH is correct. These are abnormalities restricted to the myeloma cells -- not your normal cells.

Thanks!

Pete V.

Dr. Peter Voorhees
Name: Peter Voorhees, M.D.
Beacon Medical Advisor

Re: Gene crossovers

by Jubyanne on Tue Apr 02, 2013 4:15 pm

Thank you both. As a biology major, I felt real stupid asking this question. I thought we had the same gene code in all our cells.
Julia

Jubyanne
Name: Julia Munson
Who do you know with myeloma?: myself, son's mother-in-law
When were you/they diagnosed?: Spring 2008
Age at diagnosis: 65


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