by twinkle126 on Tue Feb 03, 2015 2:58 pm
Thank you so much for your reply, Dr. Voorhees.
My hematologist told me that there are new recommendations which suggest that a high level of light chains needs treatment, but didn't explain further. Being a doctor myself, I tried to find articles about this, but didn't find anything.
I had 2 episodes of acute renal insufficiency, and they were both due to dehydration. The first one in July 2014. My serum creatinine was 4.1 mg/dl (lab norms: 0.8 - 1.2 mg/dl). The renal function was restored in about 2 weeks, And the second one in September 2014, with a serum creatinine at 6 mg/dl, but this time it was acute tubular necrosis and it took my kidneys 3 months to recover. But now my serum creatinine is fluctuating,
The doctors had such a hard time exploring this acute renal failure. I had anemia associated with it. My hemoglobin was 9.5 g/dl (norms: 12-16 g/dl), but it disappeared with iron supplements (now my hemoglobin is 12.5 g/dl).
The first Freelite assay came out negative kappa <4.5, We decided to do a second one, since the Bence Jones protein was found in my urine. It came out 720! They told me at the laboratory that they needed to dilute the serum. Note: My blood sample was coagulated, but they used it anyway for the analysis. Would that have affected the results?
My serum protein electrophoresis shows hypogammaglobulinemia
The lecture of my bone marrow aspiration showed 1 dystrophic plasmocyte.
I want to get a second opinion, but I would need to go to another country since my hematologist is the best myeloma specialist in my country.
