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Elevated total IgA levels
My IgA total is 392, ref levels 40-350. Is this a sign of multiple myeloma? All other test were in normal range.
Re: Elevated total IgA levels
Hello,
The only way to know is to have a serum electrophoresis. I would speak with your primary care physician to see if they feel this should be evaluated in more depth.
Happy Holidays.
The only way to know is to have a serum electrophoresis. I would speak with your primary care physician to see if they feel this should be evaluated in more depth.
Happy Holidays.
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Dr. Edward Libby - Name: Edward Libby, M.D.
Beacon Medical Advisor
Re: elevated total IgA levels
Thanks Doctor. I got these results but never got an explanation about findings.
Here are the readings Doctor:
Serum Protein Electrophoresis
total protein 8.0 (5.7-8.2)
albumin 4.11 (2.37-4.57)
alpha 1 - 0.39 (0.24-0.56)
apha 2- 1.11 (0.54-1.13)
beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen
gamma 1.31 (.055-1.57)
a/g ratio 1.1 (1.1-2.5)
monocional region 0.0
protein electroporesis interp. (no paraprotein detected)
Immunofixation
Keppa free light chain 16.3 (0.33-19.4)
lambda fre lighr chain 13.4 (5.7-26.3)
kappa/lamba ratio 1.2 (0.3-1.7)
Here are the readings Doctor:
Serum Protein Electrophoresis
total protein 8.0 (5.7-8.2)
albumin 4.11 (2.37-4.57)
alpha 1 - 0.39 (0.24-0.56)
apha 2- 1.11 (0.54-1.13)
beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen
gamma 1.31 (.055-1.57)
a/g ratio 1.1 (1.1-2.5)
monocional region 0.0
protein electroporesis interp. (no paraprotein detected)
Immunofixation
Keppa free light chain 16.3 (0.33-19.4)
lambda fre lighr chain 13.4 (5.7-26.3)
kappa/lamba ratio 1.2 (0.3-1.7)
Re: Elevated total IgA levels
As you can see there is no monoclonal protein and the serum free light chains are normal. These tests are strong evidence that you do not have multiple myeloma.
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Dr. Edward Libby - Name: Edward Libby, M.D.
Beacon Medical Advisor
Re: Elevated total IgA levels
Thank you again. I am concerned about the high beta fraction.
The test were done after I went to ER for bad fever and sinusitis infection, I had high ESR rate so I was sent to hematologist. He ran several test ANA, CBC, liver, automimmune liver, kidney, crp and other test. All were fine but the Beta test which was high.
Weeks later after infection ESR returned to normal but had repeated Protein electrophoresis after infection.
Any other causes other than multiple myeloma for high beta? Or is this something not to worry about. Test was done over 3 years ago and I feel absolutely fine and had several CBC, liver, kindey test done over years, all normal.
The test were done after I went to ER for bad fever and sinusitis infection, I had high ESR rate so I was sent to hematologist. He ran several test ANA, CBC, liver, automimmune liver, kidney, crp and other test. All were fine but the Beta test which was high.
Weeks later after infection ESR returned to normal but had repeated Protein electrophoresis after infection.
Any other causes other than multiple myeloma for high beta? Or is this something not to worry about. Test was done over 3 years ago and I feel absolutely fine and had several CBC, liver, kindey test done over years, all normal.
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