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Does an elevated free light chain suppress the other?

by blair77 on Sun Feb 08, 2015 4:29 pm

I'm wondering if, as one free light chain goes up, is the other free light chain suppressed?

I know this can happen with immunoglobulins, so I wondered if it worked the same way with light chains?

blair77
Who do you know with myeloma?: My husband
When were you/they diagnosed?: April 2013
Age at diagnosis: 43

Re: Does an elevated free light chain suppress the other?

by Melanie on Thu Feb 12, 2015 10:42 am

Blair,

It can happen, although not sure of the significance. We just got my husband's latest set of light chains. His lambda light chains are 2589, down from 7700. His kappa chains – which always read within normal limits – are now reading 1.86, so not sure if this is a good thing or a bad thing.

Melanie
Name: Melanie
Who do you know with myeloma?: husband
When were you/they diagnosed?: July 2014
Age at diagnosis: 54


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