In 2012 during treatment with Velcade, the oncology clinic advised me against any dental surgery or implants for a couple of years. I am in relapse, so does does this precaution apply to treatment with Empliciti (elotuzumab) and/or Kyprolis (carfilzomib)? And for how long should I be cautious?
I had only one lesion in 2011 (T1 vertebra) and nothing related in the mouth.
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hnicol3 - Name: Henry Nicol III
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 2011
- Age at diagnosis: 66
Re: Dental work during or after treatment
Are you sure if it was because you were on Velcade (bortezomib)? Were you on Aredia (pamidronate) or Zometa (zoledronic acid), both bone building drugs, at the time as well?
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Little Monkey - Name: Little Monkey
- Who do you know with myeloma?: Father-stage 1 multiple myeloma
- When were you/they diagnosed?: March/April of 2015
Re: Dental work during or after treatment
The concern with dental surgery while under treatment is that your immune system is more compromised and you therefore are more prone to infection. Apparently infection due to dental procedures puts you at greater risk.
I have not had to have any dental surgery or implants but even for routine teeth cleaning my dentist has me take an antibiotic a few hours before the appointment.
I have not had to have any dental surgery or implants but even for routine teeth cleaning my dentist has me take an antibiotic a few hours before the appointment.
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Ron Harvot - Name: Ron Harvot
- Who do you know with myeloma?: Myself
- When were you/they diagnosed?: Feb 2009
- Age at diagnosis: 56
Re: Dental work during or after treatment
Little Monkey - You are absolutely right about avoiding any type of oral surgery while on Zometa or Aredia. And as far as implants, I wouldn't consider this procedure for at least five years after taking either of these.
Ron - There are many situations (usually heart-related, but certainly for any compromised immune systems) that suggest pre-operative antibiotics for any dental procedures, including basic cleanings.
Dr. Don Hoke, retired dentist
Ron - There are many situations (usually heart-related, but certainly for any compromised immune systems) that suggest pre-operative antibiotics for any dental procedures, including basic cleanings.
Dr. Don Hoke, retired dentist
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coachhoke - Name: coachhoke
- When were you/they diagnosed?: Apri 2012
- Age at diagnosis: 71
Re: Dental work during or after treatment
I wondered if someone could share what kind of antibiotic is generally taken before dental cleanings or other dental work. This is the first I've heard of that being needed. It sounds like a good precaution.
Re: Dental work during or after treatment
Robert:
The most common broad spectrum antibiotics used prophylacticly in dentistry are amoxicillin, erythromycin, or tetracycline.
The most common broad spectrum antibiotics used prophylacticly in dentistry are amoxicillin, erythromycin, or tetracycline.
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coachhoke - Name: coachhoke
- When were you/they diagnosed?: Apri 2012
- Age at diagnosis: 71
Re: Dental work during or after treatment
A timely topic! I am going in the morning for dental cleaning. My dentist has me take amoxicillin prior to going. This is due to having taken Aredia (pamidronate) every month for a lot of years. Look up osteonecrosis of the jaw. Not a nice thing to have!
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GaryH - Name: GaryH
- Who do you know with myeloma?: Myself
- When were you/they diagnosed?: Nov./97
- Age at diagnosis: 44
Re: Dental work during or after treatment
Because I had 2 knee replacement surgeries, I always take 600 mg of antibiotic an hour before any dental treatment. There is no agreement among the medical community about whether or not one needs to keep doing that forever, but I'd rather take the antibiotic than risk an infection.
Before my multiple myeloma was discovered to be active in 2015, I had already started a dental implant process. Because my bone is fairly soft, we waited more than a year to complete the procedure. My oncologist felt strongly that he wanted to hold off on Zometa until that procedure was totally complete. According to Murphy's Law, I had 1 infusion of Zometa and then broke a bottom tooth. My oncologist consulted with the dentist and we agreed that we could go ahead since the manner in which the tooth broke allowed for a cosmetic repair that did not go near the jaw
It is always helpful when different professionals can collaborate on decision making, but I really think it is up to the patient to be vigilant also and learn as much as possible about the risks and benefits of any treatment.
Before my multiple myeloma was discovered to be active in 2015, I had already started a dental implant process. Because my bone is fairly soft, we waited more than a year to complete the procedure. My oncologist felt strongly that he wanted to hold off on Zometa until that procedure was totally complete. According to Murphy's Law, I had 1 infusion of Zometa and then broke a bottom tooth. My oncologist consulted with the dentist and we agreed that we could go ahead since the manner in which the tooth broke allowed for a cosmetic repair that did not go near the jaw
It is always helpful when different professionals can collaborate on decision making, but I really think it is up to the patient to be vigilant also and learn as much as possible about the risks and benefits of any treatment.
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barbaramh - Name: Barbara Hoffman
- Who do you know with myeloma?: me
- When were you/they diagnosed?: 1/5/2015
- Age at diagnosis: 75
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