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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Darzalex & Zometa infusions on the same day?

by DaleJC28117 on Sun Nov 24, 2019 1:09 pm

My husband is scheduled for week 7 of Darzalex on Friday. He is also scheduled for a Zometa infusion that day. The cancer center said there would not be a problem with him getting these on the same day, but I am wondering if it would be better to split them up to different days, say on his Pomalyst off week. If he gets the Zometa on Friday, this means he will have Darzalex, Pomalyst and Zometa all on the same day.

Does anyone know more whether it is okay to have Zometa and Darzalex infusions on the same day, and whether this is common or not?

Thanks in advance for your comments.

DaleJC28117
Name: Dale
Who do you know with myeloma?: Husband
When were you/they diagnosed?: 2016
Age at diagnosis: 57

Re: Darzalex & Zometa infusions on the same day?

by Nanjeanne on Mon Nov 25, 2019 9:09 am

My husband gets Zometa every 3 months and Darzalex monthly. He always does it during his Darzakex visit. In fact, all the hydration helps alleviate side effects he had with Zometa. He also takes Pomalyst 2 mg.

Nanjeanne
Name: Nanjeanne
Who do you know with myeloma?: My Husband
When were you/they diagnosed?: April 2014
Age at diagnosis: 66

Re: Darzalex & Zometa infusions on the same day?

by Robert Ancar on Mon Nov 25, 2019 9:45 am

Hello DaleJC,

On October 29, 2019 I commenced a new four-drug treatment regimen of Darzalex, Kyprolis, Pomalyst, and dexamethasone. In addition, November 6, 2019, I received my monthly 3.5 mg Zometa infusion. Three days prior I had to self-administer 3 Granix (tbo-filgrastim, similar to Neupogen) infusions (480 mcg) to boost my white blood cell count. I did not experience any adverse side effects with receiving Zometa and Darzalex the same day. But, multiple myeloma is a very heterogeneous disease. While I handled it well, others may not.

Robert Ancar
Name: Robert Ancar
Who do you know with myeloma?: Myself
When were you/they diagnosed?: May, 2017
Age at diagnosis: 61

Re: Darzalex & Zometa infusions on the same day?

by dianaiad on Mon Nov 25, 2019 11:43 am

I did it every time (the Zometa and Darzalex infusions on the same day). It was considerably more convenient, and though I did have the usual Zometa side effects, they weren't any worse for having the infusions on the same day

Strictly anecdotal and personal evidence, this, but hey, all clinical trials are collections of individual experiences, yes?

dianaiad
Who do you know with myeloma?: Me
When were you/they diagnosed?: Officially...March 2013
Age at diagnosis: 63

Re: Darzalex & Zometa infusions on the same day?

by albertlannon on Mon Nov 25, 2019 2:41 pm

I never had a problem with both on the same day.

albertlannon
Name: Albert Lannon
Who do you know with myeloma?: self
When were you/they diagnosed?: June, 2017
Age at diagnosis: 79


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