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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Is it okay to take curcumin during Darzalex treatment?

by Melpen on Thu Sep 27, 2018 1:15 pm

Does anyone know if it is safe to take curcumin when on a drug regimen of Darzalex, methyl­pred­nisolone, and Revlimid? How does curcumin interact with Darzalex?

Melpen
Name: Melissa
Who do you know with myeloma?: myself
When were you/they diagnosed?: Feb 5, 2014
Age at diagnosis: 57

Re: Is it okay to take curcumin during Darzalex treatment?

by Multibilly on Thu Sep 27, 2018 8:35 pm

Hi Melpen,

Have you asked your oncologist this question?

While I am a 6-year user of large doses of curcumin and think that it may possibly have helped keep my smoldering myeloma from advancing during this time, I would personally suspend taking any supplements if I were to undergo any sort of drug treatment for myeloma (unless my doctor specifically cleared a supplement). But that's just me. You might want to read this article:

https://www.ncbi.nlm.nih.gov/pubmed/28734960

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012

Re: Is it okay to take curcumin during Darzalex treatment?

by FingersCrossed on Sun Oct 07, 2018 1:46 pm

Multibilly,

What dose of curcumin are you on?

I am still smoldering (going on 4 years now) and have been taking 4g of curcumin daily. I've heard about some people taking up to 8g.

Thanks.

FingersCrossed
Name: FingersCrossed
Who do you know with myeloma?: Me
When were you/they diagnosed?: Oct 2014 (Smoldering)
Age at diagnosis: 44

Re: Is it okay to take curcumin during Darzalex treatment?

by Multibilly on Sun Oct 07, 2018 3:38 pm

I used to take 4g twice a day (8g per day) of regular curcumin + a 10mg bioperine tablet with each dose. I've since switched to using a C3 curcumin formulation with bioperine and I take 2g twice a day (4g per day). If you can believe some of the pseudo-scientific hype around C3 curcumin, it is supposedly more bioavailable than regular curcumin, and that's why I take a lower dose of it. C3 is a just a set combination of curcumin, demethoxycurcumin and bis-demethoxycurcumin. I'm really not sure that C3 is any better than regular curcumin, so choose your curcumin formulation accordingly ;-)

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012


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