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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Bone spurs and osteonecrosis of the jaw (ONJ)

by Pjorg45 on Mon Jul 20, 2015 8:57 am

I have been on monthly Zometa for two years and recently have had two teeth extracted. The teeth extraction has healed well and I feel great. But, I also have a small bone spur which grows out of my gum where my one tooth has been extracted. Other people here have reported similar small bone spurs (oral osteophytes) . My oral surgeon does not believe this is a sign of osteonecrosis of the jaw (ONJ).

My questions first question is: Who out there has experienced similar bone spurs, and if you had them, did you go on to have ONJ?

My second question is: Who out there has ONJ and what were the first symptoms and how long from the first symptoms to it became really bad?

Thanks,

Paul Jorgensen

Pjorg45
Name: Paul Jorgensen
When were you/they diagnosed?: May 1013
Age at diagnosis: 68

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by proudlion on Mon Jul 20, 2015 7:22 pm

Hello Paul,

My response may not be helpful but I would like to contribute my experience. I am in need of major dental work and am also receiving Zometa on a monthly basis. My oncologist forbids me from seeking any dental work without curtailing the Zometa treatments for at least eight weeks prior to the dental procedure. I am surprised that you have been permitted to obtain dental work while receiving these treatments.

The best to you,

Jerry

proudlion

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by Pjorg45 on Mon Jul 20, 2015 9:17 pm

Well I was told that I should suspend Zometta two months before and two months after the extraction. This is what I have done and I have not started Zometta again yet. In order to get a ASCT I needed dental clearance which I couldn't get without getting rid of two teeth which had bad root canels. I had no other choice. :D

Pjorg45
Name: Paul Jorgensen
When were you/they diagnosed?: May 1013
Age at diagnosis: 68

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by Jonah on Mon Jul 20, 2015 9:47 pm

Hi Paul,

I'm guessing you've seen Andrew Gordon's column from a month or two on a very similar subject. But, just in case you haven't, I think you should read it (and the comments that people made on it):

https://myelomabeacon.org/headline/2015/05/31/myeloma-lessons-this-was-a-real-surprise/

Hope the spurs turn out to be just that -- spurs, not ONJ.

Jonah

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by jrbpse on Wed Jul 22, 2015 9:50 pm

The bone spurs are not part of the jaw bone problems found in multiple myeloma, but that's simply because of the ONJ. Bone spurs are probably a result of the medication since it is designed to modify the bone growth cycle.

I discontinued my use of these type products because I considered the risk to out weigh the benefits.

jrbpse

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by Rneb on Wed Jul 22, 2015 10:06 pm

I would suggest that you confirm that you are dealing with a true "Bone Spur", as opposed to a residual tooth fragment, or a spicule of bone, loosened and de-vitalized, via the extraction process. Teeth with Bad "Root canals" , tend to come out in pieces and splinters.

Big difference between a "Bone Spur" and a perceived "foreign body" in the mandible /Maxilla. Bone spurs usually don't cause infection(s); usually they only cause local inflammation/ irritations.

Tooth fragments and Bone spicules do tend to cause secondary changes, including granualomas and frank infections/ abscesses.

This is irrespective of Zometa.

Even in the best of hands, extractions can and do, cause the above.

Good luck.

PS--Where is Coach Hoke, when you need him ?

Rneb

Re: Bone spurs and osteonecrosis of the jaw (ONJ)

by coachhoke on Wed Jul 22, 2015 11:51 pm

Rneb is probably right; it is either a bone spicule or a tooth fragment that will most likely work itself loose, similar to losing a baby tooth. (I saw hundreds of these when I was still practicing dentistry).

Secondly, ONJ is very difficult to diagnose at early stages as there are no symptoms. The only way I know to make the diagnosis is from x-rays, which I assume the oral surgeon would have taken before doing the extractions.

Coach Hoke

coachhoke
Name: coachhoke
When were you/they diagnosed?: Apri 2012
Age at diagnosis: 71


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