I have a solitary plasmacytoma, on my T7 vertebra, since November 2015. I am concerned that in the last three months my blood tests have shown increases in several areas:
RDW-CV (3.8 up)
RDW-SD (2.6 up)
Lymph% (19.4 down)
Mono% (1.6 up)
Neut% (14.4 up)
BUN (up 4)
Creatinine (0.6 up).
My research of these blood levels show they can be related to renal failure or myelodysplastic syndrome. Is this correct? Could the results be pointing to anything else?
I will be asking my oncologist this Friday, when I receive my Zometa drip, about why these levels are continuing to rise. I have also given these results to my nephrologist, who I am scheduled to see in two weeks. I am currently suffering from stage 3 kidney disease with a kidney function of 40%.
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TheQuill - Who do you know with myeloma?: No one
- When were you/they diagnosed?: Nov 16, 2015
- Age at diagnosis: 68
Re: Changing blood test results with solitary plasmacytoma
Are you receiving treatment for the plasmacytoma on your T7 vertebra?
Re: Changing blood test results with solitary plasmacytoma
I had a plasmacytoma that destroyed my T-11 in Feb 2016. I am fused from T-8 to S-2. Luckily, other than numbness from where the surgeon had to cut a major nerve in order to remove the tumor, I had no residual affects and was off all related medications. Unfortunately, the last CT scan showed multiple lytic lesions on my spine. The last round of blood tests were very good, so we were hoping that I had dodged the myeloma bullet. Getting new tests in a week – will see if things have changed.
What a ride.
What a ride.
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mtsmith - Name: mtsmith
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Feb '16
- Age at diagnosis: 56
Re: Changing blood test results with solitary plasmacytoma
Hello fellow forum members.
I have not written for a while due to my plasmacytoma being in a dormant stage. However my most recent blood tests raise a concern:
Free Kappa Lt Chain S 48.1 ref range 3.3-19.4 mg/l
Increased from 33.7 since Dec 2017.
Reading in Sept 2017 was 48.8, which was down from 53.1 in June 2017.
Free Lambda Lt Chain S. 25.2, ref range 5.7-26.3 mg/l
Increase from 23.6 since Dec 2017.
Reading in Sept 2017 was 29.9, which was up from 27.1 in June 2017.
Kappa/Lambda Ratio, S 1.91, ref range 0.26-1.65 -
Increase from 1.43 since Dec 2017.
Reading was 1.63 in Sept 2017, down from 1.96 in June 2017.
Now I have had my first M-Spike of 0.4 (with lab statement that reference range - not observed g/dl.) I know the spike is very minor, but since I have been spike free I have some concern. I see my oncologist tomorrow for my regular visit. I hope he can clarify these changes or determine if any more tests are required. I have not had a bone marrow biopsy since January of 2016.
I have not written for a while due to my plasmacytoma being in a dormant stage. However my most recent blood tests raise a concern:
Free Kappa Lt Chain S 48.1 ref range 3.3-19.4 mg/l
Increased from 33.7 since Dec 2017.
Reading in Sept 2017 was 48.8, which was down from 53.1 in June 2017.
Free Lambda Lt Chain S. 25.2, ref range 5.7-26.3 mg/l
Increase from 23.6 since Dec 2017.
Reading in Sept 2017 was 29.9, which was up from 27.1 in June 2017.
Kappa/Lambda Ratio, S 1.91, ref range 0.26-1.65 -
Increase from 1.43 since Dec 2017.
Reading was 1.63 in Sept 2017, down from 1.96 in June 2017.
Now I have had my first M-Spike of 0.4 (with lab statement that reference range - not observed g/dl.) I know the spike is very minor, but since I have been spike free I have some concern. I see my oncologist tomorrow for my regular visit. I hope he can clarify these changes or determine if any more tests are required. I have not had a bone marrow biopsy since January of 2016.
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TheQuill - Who do you know with myeloma?: No one
- When were you/they diagnosed?: Nov 16, 2015
- Age at diagnosis: 68
Re: Changing blood test results with solitary plasmacytoma
I was receiving 4 mg Zometa drip every 4 months, but stopped after December 2017 treatment.
I visited my oncologist today, and he indicated I was beginning the transition from a plasmacytoma to multiple myeloma based on my kappa increase and the 0.4 M-spike. I have been scheduled for a bone marrow biopsy on May 1. I expect I will begin the Revlimid, Velcade, and dexamethasone (RVD) treatment as soon as the results are in from the bone marrow biopsy.
While my doctor is an oncologist, I am considering starting treatment with a myeloma specialist. My doctor is open to the switch. The only hitch is the specialist is 40 miles and my doctor is 5 minutes. It seems the medication would be the same no matter who is administering.
Since I have atrial fibrillation issues and am under treatment for them, I also am wondering whether I should involve my cardiologist before I start the RVD treatments.
I appreciate all the kind thoughts and look forward to the forum for help in the future.
I visited my oncologist today, and he indicated I was beginning the transition from a plasmacytoma to multiple myeloma based on my kappa increase and the 0.4 M-spike. I have been scheduled for a bone marrow biopsy on May 1. I expect I will begin the Revlimid, Velcade, and dexamethasone (RVD) treatment as soon as the results are in from the bone marrow biopsy.
While my doctor is an oncologist, I am considering starting treatment with a myeloma specialist. My doctor is open to the switch. The only hitch is the specialist is 40 miles and my doctor is 5 minutes. It seems the medication would be the same no matter who is administering.
Since I have atrial fibrillation issues and am under treatment for them, I also am wondering whether I should involve my cardiologist before I start the RVD treatments.
I appreciate all the kind thoughts and look forward to the forum for help in the future.
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TheQuill - Who do you know with myeloma?: No one
- When were you/they diagnosed?: Nov 16, 2015
- Age at diagnosis: 68
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