[tnjmagoo]

Do these blood test results indicate possible myeloma?

by tnjmagoo on Sun Aug 16, 2015 5:54 pm

IgA 40 - 350 mg/dL 391

Tissue transglutaminase IgA <=19 unit(s) 8
Tissue transglutaminase IgA Interpretation Negative: <20

Tissue transglutaminase IgG <=19 unit(s) 3
Tissue transglutaminase IgG Interpretation Negative: <20

[Jonah]

Re: Do these blood test results indicate possible myeloma?

by Jonah on Sun Aug 16, 2015 8:16 pm

Yes. Possibly. The tissue transglutaminase tests, however, are irrelevant to figuring out whether you may have multiple myeloma or not. And lots of things can cause elevated IgA levels besides multiple myeloma or a related disease such as monoclonal gammopathy of undetermined significance (MGUS).

You would need a serum protein electrophoresis (SPEP) and serum immunofixation (IFE) to determine whether the elevated IgA is due to something such as multiple myeloma, which causes monoclonal immunoglobulins to be present in the body. Monoclonal immunoglobulins are signs of myeloma and related blood disorders. Normal immunoglobulins are polyclonal.

If you go ahead and have the SPEP and IFE tests, it might also make sense to have your serum free light chain levels tested.

Did you also get results for your other main immunoglobulins, IgG and IgM? Quantitative immunoglobulin tests usually give results for IgG, IgA, and IgM.

[Multibilly]

Re: Do these blood test results indicate possible myeloma?

by Multibilly on Sun Aug 16, 2015 8:26 pm

Tnjmagoo:

Jonah is spot on with her comments.

From these tests, I'm guessing you were tested for celiac disease, which can cause an elevated IgA. If these tests were in fact for celiac disease (which I know nothing about), have you discussed these results with the doc that ordered them and was celiac disease ruled out and were any next steps determined?