The Myeloma Beacon

Independent, up-to-date news and information for the multiple myeloma community.
Home page Deutsche Artikel Artículos Españoles

Forums

Questions and discussion to help forum members determine if they may have multiple myeloma, smoldering multiple myeloma, or MGUS.

Abnormal protein band - presence of monoclonal protein

by bvh21 on Sun Jan 15, 2017 9:58 pm

Hi,

I am 40 years old and have been dealing with joint pain and numbness in my extremities for over 2 years now. My blood work has always been fine up until this point. At first I tested for anemia, low red blood count, and a high c reactive protein. Also just had a recent kidney infection, and migraines at night. My rheumatologist ordered additional blood work (after ruling out lupus and rheumatoid arthritis) and my results were:

Abnormal protein band one 0.03
Parvovirus b19 IgG 7.8
NOTE: Possible presence of monoclonal protein

I have had no real correspondence with my doctor. because he just keeps ordering more tests due to the fact that something is always found and I have not been able to talk to him to find out what he is looking for. I called and spoke to his nurse and all she would tell me was the name of the latest test he has ordered, which is the SPEP test? I am waiting on those results now.

All of the research I have been doing keeps indicating the possibility of multiple myeloma. I am very concerned and was hoping to hear if if it seems that my doctor is testing me for a blood disorder or multiple myeloma. Any information or knowledge you can share would be beyond appreciated!

Thank you.

bvh21

Re: Abnormal protein band - presence of monoclonal protein

by Multibilly on Mon Jan 16, 2017 8:07 am

Hi bvh21,

Welcome to the forum.

It sounds like you already had an SPEP test if you have the result "Abnormal protein band one 0.03". Was this reported in g/dL? In any case, this is what is known as your "M-spike" and it came from your SPEP test. Regardless of the units of measure, 0.03 is an extremely small value, which is good news.

But you really need some other labs, such as a serum free light chain assay, quantified immuno­globulins (IgA, IgG, and IgM), and serum immunofixation test to give you a better idea if your are dealing with something such as MGUS, or another plasma cell disorder, or something else altogether.

How are your calcium and creatinine levels doing (you can find these on your comprehensive metabolic panel test results)? The aforementioned items can also sometimes be impacted by plasma cell disorders such as MGUS. The very low M-spike by itself suggests something such as MGUS, but again, you really need more tests to verify a diagnosis of a plasma cell disorder.

Hope this helps a bit.

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012


Return to Do I Have Multiple Myeloma?