Once-weekly high-dose Kyprolis led to higher response rates and longer remissions in re­lapsed / refractory myeloma patients than twice-weekly, lower-dose Kyprolis (car­filz­o­mib), interim results of the Phase 3 "ARROW" clinical trial show.

Dr. Maria-Victoria Mateos presented the trial results earlier this month at the 2018 American Society of Clinical Oncology (ASCO) annual meeting in Chicago, and also last weekend at the 2018 congress of the European Hematology Association, held in Stockholm. In addi­tion, the trial results were recently published in a medical journal (reference).

The over­all response rate to the two-drug, …

Updated re­­sults of a Phase 1 trial testing bb2121 in re­lapsed mul­ti­ple myeloma patients were pre­sented last Friday at the American Society of Clinical Oncology (ASCO) annual meeting. bb2121 is a poten­tial new myeloma treat­ment in the chi­meric an­ti­gen re­cep­tor (CAR) T-cell class of ther­a­pies.

The re­­sults pre­sented at this year's ASCO meeting con­firm pre­vi­ous findings in­di­cating bb2121 has sub­stan­tial anti-myeloma ac­­tiv­ity.

At some of the higher doses of bb2121 tested during the trial, for example, nearly every patient treated with the drug responded to it; the over­all re­sponse rate was almost …

This year’s American Society of Clinical Oncology (ASCO) annual meeting began last Friday and will run through tomorrow.

Multiple myeloma-related pre­sen­ta­tions have been taking place every day of the meeting. The main myeloma-related oral pre­sen­ta­tion session of the meeting, how­ever, took place on Friday. Research summarized during oral pre­sen­ta­tion sessions usually is par­tic­u­larly im­por­tant, either because the subject itself is im­por­tant, or because the results are based on sub­stan­tial amounts of evi­dence (for example, a sizable clin­i­cal trial).

Given the poten­tial importance of the re­search results pre­sented last Friday, The Beacon asked …

The 54th annual meeting of the American Society of Clinical Oncology (ASCO) will take place this year from June 1 to June 5 in Chicago.

Approximately 40,000 physicians, nurses, and industry rep­resentatives from all over the world are expected to attend the five-day meeting to discuss current research in cancer treat­ment and care.

During the meeting, there will be pre­sen­ta­tions about all types of cancer, in­clud­ing many pre­­sen­ta­tions focused specifically on multiple myeloma. In fact, more than 90 myeloma-related studies are scheduled to be pre­sented, in one form or another, in connection …