The results of a recent Swedish study indicate that the development of blood clots in the veins or arteries of multiple myeloma patients negatively affects survival outcomes.

The study investigators conclude that these findings warrant further studies to determine whether blood clot prevention measures can extend the survival of myeloma patients.

“There are effective ways to prevent venous and arterial thrombosis in myeloma patients; e.g, aspirin, heparin, warfarin (Coumadin), and Pradaxa (dabigatran),” said Dr. Edward Libby of the University of Washington School of Medicine in Seattle, who was not involved with the …

Celgene Corporation's German subsidiary last week issued a “Dear Health Care Professional” letter warning that thalidomide increases the risk of blood clots in arteries, which can lead to heart attacks and strokes. According to Celgene’s letter, the prescribing information for thalidomide in Europe has been updated to include a warning about this risk.

In Europe, thalidomide (Thalomid) is approved for use in combination with melphalan (Alkeran) and prednisone in newly diagnosed multiple myeloma patients over the age of 65 and newly diagnosed patients who are not candidates for stem cell transplantation. 

In the United …