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Sorafenib (Nexavar, sorafenib tosylate, BAY 43-9006)
By: Christen Brandt; Published: June 4, 2009 @ 6:56 pm | Comments Disabled
Brand Name: Nexavar
Generic Name: sorafenib tosylate
Code Name: BAY 43-9006
Company: Bayer
FDA Clinical Phase: 1, 2
Description:
Sorafenib is a kinase inhibitor that stops cells from dividing and may also prevent the growth of new blood vessels that tumors need for growth (known as angiogenesis). Sorafenib is a drug used to treat advanced kidney cancer and a type of liver cancer. It is also being studied for treating other cancers.
Clinical Trials:
Currently, there are two clinical trials with sorafenib recruiting patients. One study [1] is using a combination of Sorafenib and Everolimus. Another study is a Phase 1 trial [2] using Sorafenib in combination with Velcade (bortezomib). Both clinical trials are recruiting adults and senior patients of both genders.
Source: http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=390251
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URL to article: https://myelomabeacon.org/resources/treatments-under-development/2009/06/04/sorafenib-nexavar-sorafenib-tosylate-bay-43-9006/
URLs in this post:
[1] study: http://clinicaltrials.gov/ct2/show/NCT00474929?term=Sorafenib&recr=Open&rank=174
[2] trial: http://clinicaltrials.gov/ct2/show/NCT00303797?term=Sorafenib&recr=Open&rank=178
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