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Sorafenib (Nexavar, sorafenib tosylate, BAY 43-9006)

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Published: Jun 4, 2009 6:56 pm

Brand Name: Nexavar
Generic Name: sorafenib tosylate
Code Name: BAY 43-9006
Company: Bayer
FDA Clinical Phase: 1, 2

Description:
Sorafenib is a kinase inhibitor that stops cells from dividing and may also prevent the growth of new blood vessels that tumors need for growth (known as angiogenesis). Sorafenib is a drug used to treat advanced kidney cancer and a type of liver cancer. It is also being studied for treating other cancers.

Clinical Trials:
Currently, there are two clinical trials with sorafenib recruiting patients. One study is using a combination of Sorafenib and Everolimus.  Another study is a Phase 1 trial using Sorafenib in combination with Velcade (bortezomib). Both clinical trials are recruiting adults and senior patients of both genders.

Source: http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=390251

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