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ACE-011 (sotatercept)

By: Alyssa Liguori; Published: December 26, 2009 @ 5:24 pm | Comments Disabled

Brand Name:
Generic Name: sotatercept
Code Name: ACE-011
Company: Celgene and Acceleron Pharma
FDA Clinical Phase: 2

Description:

ACE-011 is a human fusion protein from the combination of Activin Receptor Type IIA and an antibody molecule. It is called a fusion protein because scientists have joined two different genes, each of which typically code for separate proteins. By fusing the genes, a new, unique protein is created with certain functions from both of the original proteins. This fusion protein, ACE-011, inhibits bone loss and promotes bone formation.

Clinical Trials:
For a list of clinical trials studying ACE-011 for the treatment of multiple myeloma, see ClinicalTrials.gov [1].

Web site for ACE-011: http://www.acceleronpharma.com [2].

Updated December 26, 2009

Article printed from The Myeloma Beacon: https://myelomabeacon.org

URL to article: https://myelomabeacon.org/resources/2009/12/26/ace-011/

URLs in this post:

[1] ClinicalTrials.gov: http://www.clinicaltrials.gov/ct2/results?term=ACE-011&recr=&rslt=&type=&cond=myeloma&intr=&outc=&lead=&spons=&id=&state1=&cntry1=&state2=&cntry2=&state3=&cntry3=&locn=&gndr=&rcv_s=&rcv_e=&lup_s=&lup_e=

[2] http://www.acceleronpharma.com: http://www.acceleronpharma.com/content/products/ace-011.jsp

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