ACE-011 (sotatercept)

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Published: Dec 26, 2009 5:24 pm
Brand Name:
Generic Name: sotatercept
Code Name: ACE-011
Company: Celgene and Acceleron Pharma
FDA Clinical Phase: 2

Description:

ACE-011 is a human fusion protein from the combination of Activin Receptor Type IIA and an antibody molecule. It is called a fusion protein because scientists have joined two different genes, each of which typically code for separate proteins. By fusing the genes, a new, unique protein is created with certain functions from both of the original proteins. This fusion protein, ACE-011, inhibits bone loss and promotes bone formation.

Clinical Trials:
For a list of clinical trials studying ACE-011 for the treatment of multiple myeloma, see ClinicalTrials.gov.

Web site for ACE-011: http://www.acceleronpharma.com.

Updated December 26, 2009
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