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[Jun 8, 2012 8:09 pm | One Comment]
Extensive Carfilzomib Clinical Trial Results Presented (ASCO 2012)

Results from a number of clinical trials studying car­filz­o­mib for the treat­ment of multiple myeloma were presented at the 2012 American Society of Clinical Oncology (ASCO) annual meeting last weekend.

Findings from three Phase 1/2 clinical trials showed that several carfilzomib (Kyprolis) com­bi­na­tions are effective for newly diagnosed multiple myeloma patients. Researchers involved in each of these clinical trials presented the results during oral presentations at the ASCO meeting.

In addi­tion, early results from …

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[Jun 7, 2012 3:13 pm | 3 Comments]
Daratumumab Shows Promise As Treatment For Relapsed / Refractory Multiple Myeloma (ASCO 2012)

Interim results of an ongoing early-stage clin­i­cal trial indicate that dara­tu­mu­mab is safe as a treat­ment for re­lapsed and refractory multiple myeloma. In addi­tion, dara­tu­mu­mab showed promising activity in the trial par­tic­i­pants.

Dr. Torben Plesner of Vejle Hospital in Denmark presented the pre­lim­i­nary results of the Phase 1/2 study at the 48th annual meeting of the American Society of Clinical Oncology (ASCO) on Monday.

“The efficacy [of dara­tu­mu­mab] looks very promising,” said Dr. Andrzej Jakubowiak, the director of the myeloma …

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[Jun 6, 2012 3:13 pm | 40 Comments]
Arnie’s Rebounding World: The Roller Coaster Ride

I have taken a few months off from writing my column to deal with my multiple myeloma health issues and to sort out my next steps.

Most of The Myeloma Beacon’s columnists are upbeat, positive, or even humorous.  I was feeling none of those things.  Most of the emotions I was having were too unsettled, confusing, and raw to write about.

The last few months have been a roller coaster of ups and downs.  At least for now, the dust …

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[Jun 5, 2012 9:13 pm | One Comment]
ASCO 2012 Multiple Myeloma Update – Day Four: Poster Presentations On Various Myeloma-Related Topics

Today is the last day of this year’s American Society of Clinical Oncology (ASCO) annual meeting, which is being held in Chicago. However, the multiple myeloma-related presentations at the meeting concluded yesterday.

A poster session yesterday afternoon featured research on a wide variety of myeloma-related topics, ranging from new treatments being developed for myeloma, to currently used regimens, to second cancers, to precursor myeloma diseases, and much more.

This article summarizes research from that session related to prognostic factors, precursor myeloma …

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[Jun 5, 2012 3:50 pm | Comments Off]
ASCO 2012 Multiple Myeloma Update – Day Four: Poster Presentations On Current Myeloma Treatments

Today concludes this year’s American Society of Clinical Oncology (ASCO) annual meeting, which began on Friday in Chicago.  However, yesterday was the last day with any multiple myeloma-related sessions.

During yesterday’s poster session, important new research findings were summarized on posters throughout a large conference hall.

The studies were on a wide variety of myeloma-related topics ranging from new treatments being developed for myeloma, to currently used regimens, to secondary cancers, to precursor myeloma diseases, and much more.

This update …

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[Jun 4, 2012 8:23 pm | 7 Comments]
ASCO 2012 Multiple Myeloma Update – Day Four: Poster Presentations On New Myeloma Treatments

This year’s American Society of Clinical Oncology (ASCO) annual meeting, which is being held in Chicago, began on Friday and goes through tomorrow. How­ever, to­day is the last day with any myeloma-related sessions.

Several myeloma-related oral pre­sen­ta­tions were given this morn­ing and were summarized in an up­date pub­lished earlier to­day (see re­lated Beacon news).

This afternoon featured a poster session in which im­por­tant new re­search findings were summarized on posters throughout a large conference hall.

The stud­ies pre­sented this afternoon …

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[Jun 4, 2012 5:28 pm | 10 Comments]
ASCO 2012 Multiple Myeloma Update – Day Four: Immunotherapy For Myeloma

Today is the fourth day of the American Society of Clinical Oncology (ASCO) 2012 annual meeting, and the meeting con­tinued to be filled with in­ter­est­ing re­­sults from clin­i­cal trials in mul­ti­ple myeloma patients.

The day in­cluded a session of oral pre­sen­ta­tions in the late morn­ing that featured re­­sults from three clin­i­cal trials involving immuno­therapy agents.

The three com­pounds, elotuzumab, siltuximab, and daratumumab, belong to the class of drugs called mono­clonal anti­bodies. They work by identifying pro­teins on …