[suzierose]

No Cross-Resistance between Pom and Lenalidamide

by suzierose on Wed Dec 12, 2012 1:59 am

At 2012 ASCO Dr. Vij, presented data showing pomalidomide works in lenalidomide and Bort refractory patients, even those who have failed SCT.

POM, given at 4 mg/day on days 1–21 of each 28-day cycle in combination with LoDEX, 40 mg/week, is effective in pts with RRMM refractory to LEN, BORT, or both, and including those with prior transplant. These results suggest a lack of cross-resistance between POM and LEN, and confirm activity not only in BORT-refractory pts but also those for whom transplant has failed.

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=114&abstractID=100148

[Stann]

Re: No Cross-Resistance between Pom and lenalidomide

by Stann on Thu Dec 13, 2012 1:49 pm

excellent news!