"Single-agent CFZ demonstrated clinically meaningful, durable responses in pts with double-refractory/intolerant multiple myeloma or disease refractory to all 5 approved classes of treatment. The ORRs across groups of clinical interest were generally consistent with results for the entire study population. These results are notable for a next-generation PI and demonstrate the activity of single-agent CFZ in pts with advanced stage multiple myeloma."
http://abstract.asco.org/AbstView_114_94418.html
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