[TerryH]

TG02 - potential new myeloma treatment

by TerryH on Tue Apr 03, 2012 5:20 am

I just came across information about a potential new treatment for myeloma, called TG02.

Here is a technical description of the drug at the website of the company developing it:

http://www.tragarapharma.com/dev_tg02.htm

It's being called a "multi kinase inhibitor", and supposedly it would be the first of its kind in its class when it comes to the treatment of myeloma.

There is a Phase 1 trial currently testing the drug to determine its appropriate dose. Here is information about the trial:

http://clinicaltrials.gov/ct2/show/NCT01204164

For the technically inclined, I also found this poster from the ASH 2010 annual meeting that describes a number of laboratory tests done to measure the drug's activity against myeloma:

"Antimyeloma Action of the Multikinase Inhibitor TG02"

The authors of the poster feel their tests indicate the drug has strong anti-myeloma activity. Of course, the real test comes when the drug is tested with actual patients, which is why it will be interesting to see what happens in the drug's Phase 1 trial.