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Questions and discussion about smoldering myeloma (i.e., diagnosis, risk of progression, potential treatment, etc.)

Myeloma as a symptom?

by Jacqueline on Tue Jan 26, 2016 7:46 am

Hello,

Is it possible that the multiple myeloma would be "only" a symptom of an underlying disease, a not-yet-detected deep cancer, for example?

That is just a question (I didn't find a reply on the Internet).

Thanks

Jacqueline
Name: Jacqueline
When were you/they diagnosed?: november 2010
Age at diagnosis: 53

Re: Myeloma as a symptom?

by Little Monkey on Tue Jan 26, 2016 8:34 am

Bonjour Jacqueline,

I don't think anyone will argue with you that such may be a possibility; there are things that are not fully understood yet about myeloma / plasma cell illnesses.

Little Monkey
Name: Little Monkey
Who do you know with myeloma?: Father-stage 1 multiple myeloma
When were you/they diagnosed?: March/April of 2015

Re: Myeloma as a symptom?

by CathyAnn on Mon Feb 08, 2016 10:37 pm

I am a physician but not one that specializes in hematology. I am also a smoldering myeloma patient. Symptoms are things that a patient will feel (such as fatigue, pain, nausea, rashes, fever, cough, etc.). Myeloma is a disease, not a symptom. It has a set of diagnostic test abnormalities that are required to make the diagnosis. Some of those abnormal tests can result in symptoms (for example, bone lesions causing pain or anemia causing fatigue). But many patients with myeloma have abnormal tests but no symptoms. So I don't think you could say that myeloma is a symptom of another disease.

If you are asking if the abnormal tests that lead to a diagnosis of myeloma could be signs of another underlying problem that causes the myeloma, well, that I couldn't say for sure. From what I have read, it seems that the event that is the "first domino" is one of the gene translocations or deletions that starts the abnormal cells to grow and produce abnormal proteins. But the change in the cell's DNA that leads to developing the disease of myeloma wouldn't be considered a separate disease from the myeloma.

Does that help answer your question?

CathyAnn
Name: CathyAnnCleveland
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 1/22/2016
Age at diagnosis: 56

Re: Myeloma as a symptom?

by Jacqueline on Tue Feb 16, 2016 11:59 am

Thank you very much, CathyAnn. It is clear now for me.

Jacqueline
Name: Jacqueline
When were you/they diagnosed?: november 2010
Age at diagnosis: 53

Re: Myeloma as a symptom?

by CathyAnn on Tue Feb 16, 2016 12:13 pm

Happy to help.

CathyAnn
Name: CathyAnnCleveland
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 1/22/2016
Age at diagnosis: 56


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