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Daratumumab (Darzalex) is working for me

by MikeJBaron on Sat Nov 14, 2015 11:06 am

I've recently completed my second cycle of the "study drug" daratumumab at the UNC Cancer Hospital in Chapel Hill, North Carolina. This "study" is at 40 cancer centers across the US and consists of 300 to 400 relapsed multiple myeloma patients who have failed other chemos.

Daratumumab is "knocking it out of the park" for me! Not only are my numbers dropping radically, but I am not experiencing ANY of the terrible side effects of other multiple myeloma chemos.

This seems to good to be true! I am praying that daratumumab keeps on working and takes me to remission.

Mike J DaratumumaBaron
Winston-Salem, NC

MJBaronDaraResults2.jpg
MJBaronDaraResults2.jpg (202.71 KiB) Viewed 4022 times

MikeJBaron
Name: Mike J Baron
Who do you know with myeloma?: I have myeloma
When were you/they diagnosed?: 2004
Age at diagnosis: 56
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Re: Daratumumab (Darzalex) is working for me

by Multibilly on Sat Nov 14, 2015 11:32 am

But wait, there's more! And boy, can it catch fish! LOL at your graphics.

That's really great news and personally encouraging to me since I am really hoping that monoclonal antibodies ("mabs") will be the next big short-term breakthrough treatment for multiple myeloma. Please keep us updated on how things progress over time.

BTW, which drug cocktail are you on with the daratumumab?

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012
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Re: Daratumumab (Darzalex) is working for me

by Bar-none on Sat Nov 14, 2015 11:36 am

Great news Mike and thank the Lord!

I really like your graphics and keep up the good news! Keep us posted!

Best! BN

Bar-none
Who do you know with myeloma?: Me
When were you/they diagnosed?: 3/14
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Re: Daratumumab (Darzalex) is working for me

by brandyjoco on Sat Nov 14, 2015 11:39 am

Mike,

Thank you so much for posting this. I so appreciate this, as my husband is recently diagnosed as smoldering multiiple myeloma and we find out this week if his PET/CT shows lesions (the xrays had some possible issues show up).

Please keep us updated on your progress. Thank you again for giving us hope ...

brandyjoco
Name: brandyjoco
Who do you know with myeloma?: husband
When were you/they diagnosed?: September 2015
Age at diagnosis: 54
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Re: Daratumumab (Darzalex) is working for me

by Little Monkey on Sat Nov 14, 2015 3:06 pm

Happy to hear daratumumab is working for you :D

Little Monkey
Name: Little Monkey
Who do you know with myeloma?: Father-stage 1 multiple myeloma
When were you/they diagnosed?: March/April of 2015
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Re: Daratumumab (Darzalex) is working for me

by FingersCrossed on Sat Nov 14, 2015 7:26 pm

Great news! I've heard daratumumab shows a lot of promise. It's nice to see a concrete example of success.

FingersCrossed
Name: FingersCrossed
Who do you know with myeloma?: Me
When were you/they diagnosed?: Oct 2014 (Smoldering)
Age at diagnosis: 44
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Re: Daratumumab (Darzalex) is working for me

by brandyjoco on Mon Nov 16, 2015 3:38 pm

Daratumumab is approved!

"Darzalex (Daratumumab) Approved By FDA For Multiple Myeloma," The Myeloma Beacon

brandyjoco
Name: brandyjoco
Who do you know with myeloma?: husband
When were you/they diagnosed?: September 2015
Age at diagnosis: 54
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Re: Daratumumab (Darzalex) is working for me

by lbbiddy on Thu Nov 19, 2015 3:45 pm

I am so happy for you!

My 82-year-old mom is currently in the trial for daratumumab and will stay until the other Emory locations are set up with the drug. After three treatments her numbers have dropped dramatically. Her IgG was 3200 and has dropped to 2080. Kappa and paraprotein have also had a huge decrease.

The bad side is she had to have a metal bar placed in her leg yesterday to support the myeloma damaged hip/thigh bone. I never thought she would see a remission but you never know. This will be a great Thanksgiving and Christmas.

Lisa

lbbiddy
Name: Lisa Biddy
Who do you know with myeloma?: Mom
When were you/they diagnosed?: 2013
Age at diagnosis: 80
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Re: Daratumumab (Darzalex) is working for me

by MikeJBaron on Sat Nov 21, 2015 10:31 am

Multibilly wrote:
But wait, there's more! And boy, can it catch fish! LOL at your graphics.

That's really great news and personally encouraging to me since I am really hoping that monoclonal antibodies ("mabs") will be the next big short-term breakthrough treatment for multiple myeloma. Please keep us updated on how things progress over time.

BTW, which drug cocktail are you on with the daratumumab?

Mike's answers:

1. Yes, daratumumab not only CATCHES FISH when I soak my tackle in it, but when I add daratumumab to my gas tank, my Toyota gets 8 more miles per gallon!

2. There is no "drug cocktail" with the daratumumab. I suppose you were thinking something like daratumumab + Revlimid. Nope. It is just daratumumab + dex.

Update: Now that daratumumab has become FDA approved, this Phase IV drug study I am part of will end immediately. Daratumumab was free in this study, but FDA approved means now my two health insurance plans will need to begin paying for daratumumab.

Hmmmm ... I wonder how much daratumumab will cost? Dara to take a guess?

MikeJBaron
Name: Mike J Baron
Who do you know with myeloma?: I have myeloma
When were you/they diagnosed?: 2004
Age at diagnosis: 56
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Re: Daratumumab (Darzalex) is working for me

by BeatMyeloma on Tue Nov 24, 2015 7:05 pm

Hi Mike,

Looks like you're a long time patient. What things were you on before daratumumab?

BeatMyeloma
Name: BeatMyeloma
Who do you know with myeloma?: My mother
When were you/they diagnosed?: Jan. 2008
Age at diagnosis: 54
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