EHA 2018 Multiple Myeloma Abstracts –
Poster Presentations On June 16
There will be two sessions at the 2018 European Hematology Association (EHA) meeting where posters focused on multiple myeloma-related research will be displayed and visitors to the poster hall can speak with one of the poster's authors. The first session will be in the late afternoon on Friday, June 15. The second will be in the late afternoon on Saturday, June 16.
Listed below are titles and links to the abstracts for the myeloma-related posters that will be on display on Saturday, June 16. A separate list is available for posters to be presented on Friday, June 15. Both lists include transplantation-related posters with either direct or indirect relevance to multiple myeloma.
The Beacon also has a list of EHA 2018 myeloma-related "e-posters" and a list of all myeloma-related oral presentations.
Links to PDF files containing posters will be added to entries in this list as those files are made available to The Beacon courtesy of the EHA presenters.
| Session | Gene Therapy, Cellular Immunotherapy and Vaccination – Biology & Translational Research |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1148 – Novel RNA Construct Increases Perforin And Granzyme B In Natural Killer And Cytotoxic T Cells
Arnika Wagner, Michael Chrobok, Alamdar Hussain Baloch, Carin Dahlberg, Hareth Nahi, Hans-Gustaf Ljunggren, Evren Alici (abstract)
PS1154 – High Baseline Ferritin Is Associated With Grade 2 CRS Requiring Tocilizumab Or Grade ≥ 3 CRS In Relapsed / Refractory Multiple Myeloma Patients Treated With bb2121 Anti-BCMA CAR T Cells
Jesus Berdeja, Yi Lin, James N. Kochenderfer, Noopur Raje, Nikhil Munshi, David Siegel, Michaela Liedtke, Deepu Madduri, Jacalyn Rosenblatt, Marcela Maus, Ashley Turka, Lyh Ping Lam, Kristen Hege, Timothy Campbell, Monica Massaro, Fabio Petrocca, Sundar Jagannath (abstract)
PS1155 – The Combination Of CD19/BCMA-Directed CART Cells Induced Therapeutic Response And Reversible Compartmental Cytokine Release Syndrome Confined To Cerebral Region In A Patient With CNS Multiple Myeloma
Caixia Li, Jia Chen, Ying Zhang, Jin Zhou, Jingren Zhang, Dan Yang, Pu Wang, Changfeng Zhang, Chengcheng Fu, Depei Wu (abstract)
| Session | Infectious Diseases, Supportive Care |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1198 – One-Year Survival Among Patients With Hematological Disease Admitted To The Intensive Care Unit: A Nationwide Cohort Study
Peter Asdahl, Steffen Christensen, Anders Kjaersgaard, Christian Fynbo Christiansen, Peter Kamper (abstract)
PS1213 – Characteristics Of Hematological Patients With Blood Cultures Proven Sepsis – Experience Of One Center
Karla Misura Jakobac, Njetocka Gredelj Simec, Viktor Zatezalo, Iva Butic, Antonio Hanzek, Delfa Radic Kristo, Slobodanka Ostojic Kolonic (abstract)
| Session | Myeloma and Other Monoclonal Gammopathies – Biology & Translational Research |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1260 – TLR4 Signaling Drives Mesenchymal Stem Cells (MSC) Commitment To Promote Tumor Microenvironment Transformation In Multiple Myeloma
Cesarina Giallongo, Daniele Tibullo, Giuseppina Camiolo, Nunziatina L Parrinello, Piera La Cava, Alessandra Romano, Fabrizio Puglisi, Enrica Martino, Giuseppe Sapienza, Concetta Conticello, Giuseppe A Palumbo, Francesco Di Raimondo (abstract)
PS1262 – Bi-Allelic Loss Of FAM46C By CRISPR / Cas9 System Enhances Myeloma Cell Growth
Jo Kanasugi, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Shohei Mizuno, Kaori Uchino, Susumu Suzuki, Yoshitaka Hosokawa, Akiyoshi Takami (abstract)
PS1263 – A High Level Of Genomic Complexity Correlates With Advanced Plasma Cell Differentiation Stages In Newly Diagnosed MM Patients
Marina Martello, Rosalinda Termini, Barbara Santacroce, Enrica Borsi, Vincenza Solli, Chiara Benni, Andrea Poletti, Lucia Pantani, Beatrice Anna Zannetti, Serena Rocchi, Elena Zamagni, Paola Tacchetti, Francesca Ulbar, Mario Arpinati, Gabriella Chirumbolo, Nicoletta Testoni, Giovanni Martinelli, Michele Cavo, Carolina Terragna (abstract)
PS1264 – Molecular Segmentation Of Multiple Myeloma By Integrative Multi-omics Analysis
Maria Ortiz Estevez, Mehmet Samur, Fadi Towfic, Konstantinos Mavrommatis, Erin Flynt, Brian A. Walker, Matthew Trotter, Gareth Morgan, Nikhil Munshi, Anjan Thakurta (abstract)
PS1265 – Systematic Identification Of Pharmacogenomics Interactions Modulating Drug Responses In Multiple Myeloma
Muntasir Mamun Majumder, Muhammad Ammad-ud-din, David Tamborero, Pekka Anttila, Raija Silvennoinen, Samuli Eldfors, Juha Lievonen, Alun Parsons, Minna Suvela, Nuria Lopez Bigas, Pekka Martinen, Esa Jantunen, Samuel Kaski, Kimmo Porkka, Caroline Heckman (abstract)
PS1266 – ADAR1-Mediated-NEIL1 Editing Is Of Biological Significance In Multiple Myeloma
Phaik Ju Teoh, Omer An, Tae-Hoon Chung, Henry Yang, Wee Joo Chng (abstract)
PS1267 – Detection Of MYD88 And CXCR4 Mutations In Cell-Free DNA Of Patients With IgM Monoclonal Gammopathies
Tina Bagratuni, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Nefeli Mavrianou-Koutsoukou, Christine Liacos, Dimitrios Patseas, Nikolaos Kanellias, Magdalini Migkou, Dimitrios Ziogas, Evangelos Eleutherakis-Papaiakovou, Maria Roussou, Despina Fotiou, Evangelos Terpos, Kastritis Efstathios, Meletios Dimopoulos (abstract)
PS1268 – Next-Generation Sequencing Alternatives For The Detection And Quantification Of Minimal Residual Disease In Multiple Myeloma Patients
Alejandro Medina, Cristina Jiménez, Noemí Puig, Beatriz Sánchez-Vega, Marcos González, Rosa M Ayala, María Eugenia Sarasquete, Bruno Paiva, Teresa Cedena, Inmaculada Rapado, Laura Rosiñol, Enrique Ocio, Albert Oriol, Jeffrey Miller, Fuensanta Martínez-Rucobo, Miguel T Hernández, Rafael Martínez, María Victoria Mateos, Juan José Lahuerta, Joan Blade, Jesús F San Miguel, Joaquín Martínez-López, Ramón García-Sanz (abstract)
PS1269 – Iron Increases The Efficacy Of Standard Multiple Myeloma Therapy In Transgenic Vk*MYC Model
Jessica Bordini, Maurilio Ponzoni, Magda Marcatti, Clara Camaschella, Alessandro Campanella (abstract)
PS1270 – Bone Marrow Macrophages In Patients With Multiple Myeloma In Complete Remission Retain Pro-Tumor M2 Phenotype
Ester Lozano, Tania Diaz, Mari-Pau Mena, Maria Teresa Cibeira, Ignacio Isola, Laura Rosinol, Joan Blade, Carlos Fernandez de Larrea (abstract)
PS1271 – PTC-028 Demonstrates Potent Pre-clinical Activity And Provides A Novel Opportunity To Modulate BMI1 In Multiple Myeloma
Arnold Bolomsky, Joséphine Muller, Kathrin Stangelberger, Roy Heusschen, Marla Weetall, Art Branstrom, Niklas Zojer, Jo Caers, Heinz Ludwig (abstract)
PS1272 – Arginine Deprivation Sustains Plasma Cell Fitness And Bioenergetics In Multiple Myeloma
Alessandra Romano, Laura Oliva, Nunziatina Laura Parrinello, Jose Manteiga, Piera La Cava, Katia Todoerti, Cesarina Giallongo, Daniele Tibullo, Giuseppina Camiolo, Fabrizio Puglisi, Claudia Bellofiore, Ugo Orfanelli, Matteo Trudu, Concetta Conticello, Giuseppe Alberto Palumbo, Fabio Ciceri, Giovanni Tonon, Roberto Sitia, Simone Cenci, Francesco Di Raimondo (abstract)
PS1273 – Demethylation Sensitises T(4;14) Multiple Myeloma To RAS-MAPK Pathway Inhibition
Jay Hocking, Andrew Spencer, Sridurga Mithraprabhu, Tiffany Khong (abstract)
PS1274 – CD96 (TACTILE) Negatively Regulates The Cytotoxic Functions Of Natural Killer Cells Against Multiple Myeloma
Tony Duggan, Subhashis Sarkar, Sachin Chauhan, John Daly, Michael O'Dwyer (abstract)
PS1275 – Glutamine-Dependence Targeting By Asparaginase Significantly Increases Anti-MM Activity Of Proteasome Inhibition
Paola Minetto, Debora Soncini, Antonia Cagnetta, Fabio Guolo, Veronica Retali, Samantha Ruberti, Giulia Rivoli, Nadia Bisso, Nikki Di Felice, Maurizio Miglino, Letiza Canepa, Marco Gobbi, Roberto Massimo Lemoli, Michele Cea (abstract)
PS1276 – Mitochondrial Activity Plays A Critical Role In Multiple Myeloma Resistance
Alejandra Ortiz, Yanira Ruiz-Heredia, Mª Luz Morales, Carmen Barcenas, Rosa María García-Martin, Vanesa Garrido, Irene Baquero, Rafael Alonso, Joaquin Martínez-López, María Linares, Miguel Gallardo (abstract)
PS1277 – Elotuzumab Promotes Self-Engagement Of SLAMF7 Between Natural Killer And Multiple Myeloma Cells To Enhance Cytotoxicity
Tatiana Pazina, Ashley M. James, Amy Jhatakia, Robert F. Graziano, Natalie A. Bezman, Michael D. Robbins, Adam D. Cohen, Kerry S. Campbell (abstract)
PS1278 – Carfilzomib-Induced Cardiotoxicity: Molecular Mechanisms And The Emerging Role Of Metformin As A Prophylactic Therapy
Georgios Kremastiotis, Panagiotis Efentakis, Aimilia Varela, Constantinos H. Davos, Eleni-Dimitra Papanagnou, Ioannis P. Trougakos, Efstathios Kastritis, Zoi Kanaki, Efstathios Iliodromitis, Apostolos Klinakis, Meletios A. Dimopoulos, Ioanna Andreadou, Evangelos Terpos (abstract)
PS1279 – Jagged1/2 Inhibition Promotes Tumor Cells Response To Bortezomib In A Zebrafish Model Of Multiple Myeloma
Michela Colombo, Mara Mazzola, Raffaella Colella, Silvia Garavelli, Maria Teresa Palano, Domenica Giannandrea, Natalia Platonova, Antonino Neri, Anna Pistocchi, Raffaella Chiaramonte (abstract)
PS1280 – TGFΒ Inhibition In Combination With Chemotherapy Repairs Existing Lytic Bone Lesions In A Novel Plateau Phase Model Of Multiple Myeloma
Andrew Chantry, Green Alanna, Down Jenny, Evans Holly, Julia Paton-Hough, Snowden John, Lawson Michelle (abstract)
PS1281 – Multiple Myeloma: Single Platform Absolute Count Of Circulating Plasma Cells At Diagnosis Correlate With Poor Prognosis Parameters.
Vittorio Emanuele Muccio, Milena Gilestro, Elona Saraci, Stefano Spada, Marina Ruggeri, Simona Caltagirone, Daniela Oddolo, Michele Cavo, Vincenzo Pavone, Sonia Ronconi, Donatella Vincelli, Anna Maria Cafro, Claudia Cellini, Caterina Musolino, Stefano Molica, Annalisa Bernardini, Francesca Gay, Pellegrino Musto, Mario Boccadoro, Paola Omedé (abstract)
PS1282 – Multiple Myeloma Pathogenesis: The Role Of JunB In Bone Marrow Angiogenesis
Stefano Malvestiti, Fengjuan Fan, Hasan Muhammad Bashari, Eugenio Morelli, Anja Seckinger, Dirk Hose, Hartmut Goldschmidt, Inka Zoernig, Latifa Bakiri, Martin Sattler, Sonia Vallet, Martin Pecherstorfer, Erwin Friedrich Wagner, Pierfrancesco Tassone, Dirk Jaeger, Klaus Podar (abstract)
PS1283 – Targeted Liposomal Multi-Drug Delivery To Tumor-Associated Endothelium As A Novel Strategy To Reverse Microenvironment-Induced Drug Resistance In Multiple Myeloma
Cinzia Federico, Barbara Muz, Feda Azab, Pilar de la Puente, Jennifer Sun, Kinan Alhallak, Justin King, Vaishali Kapoor, Aldo Roccaro, Dinesh Thotala, Dennis E. Hallahan, Samuel Achilefu, Ravi Vij, Abdel Kareem Azab (abstract)
PS1284 – WNT/Β-Catenin And Hedgehog Inhibitors As Therapeutic Approaches In B-Cell Neoplasms
Catarina Ferreira, Joana Jorge, Raquel Alves, Ana Cristina Gonçalves, Ana Bela Sarmento Ribeiro (abstract)
PS1285 – Multiple Myeloma Induces Changes In Bone Marrow Adipocytes In Vitro And In Vivo
Michaela Reagan, Carolyne Falank, Mariah Farrell, Michelle McDonald, Peter Croucher, Heather Fairfield (abstract)
PS1286 – Protein Kinase CK1 Alpha Modulates Prosurvival Autophagy In Multiple Myeloma
Marilena Carrino, Sabrina Manni, Laura Quotti Tubi, Sara Canovas Nunes, Ketty Gianesin, Gregorio Barilà, Livio Trentin, Renato Zambello, Gianpietro Semenzato, Francesco Piazza (abstract)
PS1287 – Serum Lipid Metabolomics As A Useful Biomarker Predicting For The Efficacy Of Bortezomib Treatment And Peripheral Neuropathy In Patients With Multiple Myeloma
Masaki Ri, Keiko Maekawa, Miki Nakajima, Akihiro Sekine, Ryuzo Ueda, Masahiro Tohkin, Naoki Miyata, Yoshiro Saito, Shinsuke Iida (abstract)
PS1288 – Circulating Soluble Urokinase-Type Plasminogen Activator Receptor Levels Reflects Renal Function In Newly Diagnosed Patients With Multiple Myeloma Who Are Treated With Bortezomib-based Therapy
Evangelos Terpos, Gerasimos-Petros Papassotiriou, Efstathios Kastritis, Alexandra Margeli, Nikolaos Kanellias, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Erasmia Psimenou, Ioannis Papassotiriou, Meletios A. Dimopoulos (abstract)
PS1290 – Evaluation Of The Activity Of IMiDs In MM Proliferating Cells
Joan Ballesteros, Bartosz Puła, Robak Paweł, Adam Walter-Croneck, Agnieszka Druzd-Sitek, Dominik Dytfeld, Joaquín Martínez López, Pilar Hernández, Julian Gorrochategui, Jose Luis Rojas, Daniel Primo, Krzysztof Jamroziak (abstract)
| Session | Myeloma and Other Monoclonal Gammopathies – Clinical |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1291 – Addition Of Vorinostat To Lenalidomide Maintenance In Newly Diagnosed Myeloma Does Not Improve Outcomes: Results Of The Myeloma XI Trial
Matthew Jenner, Alina Striha, Faith Davies, David Cairns, Charlotte Pawlyn, John Jones, Bhuvan Kishore, Mamta Garg, Cathy Williams, Kamaraj Karunanithi, Jindriska Lindsay, Nigel Russell, Gordon Cook, Mark Drayson, Martin Kaiser, Roger Owen, Walter Gregory, Gareth Morgan, Graham Jackson (abstract)
PS1292 – Pomalidomide + Low-Dose Dexamethasone + Daratumumab In Patients With Relapsed And / Or Refractory Multiple Myeloma After Lenalidomide-Based Treatment Failure
David S. Siegel, Gary J. Schiller, Christy Samaras, Michael Sebag, Jesus Berdeja, Siddharta Ganguly, Jeffrey Matous, Kevin Song, Christopher S. Seet, Giampaolo Talamo, Shanti Srinivas, Mirelis Acosta-Rivera, Michael Bar, Donald Quick, Bertrand Anz, Gustavo Fonseca, Donna Reece, Faiza Zafar, Weiyuan Chung, Nizar J. Bahlis (abstract)
PS1293 – Doublet vs Triplet Lenalidomide-Containing Regimens Followed By Maintenance: Subgroup Analysis By Frailty Status After A Median Follow-Up Of 5 Years (EMN01 Phase III Study)
Sara Bringhen, Nicola Giuliani, Alessandro Rambaldi, Francesca Bonello, Stelvio Ballanti, Patrizia Tosi, Angelo Belotti, Fabrizio Ciambelli, Simona Caltagirone, Sonia Ronconi, Anna Maria Cafro, Clotilde Cangialosi, Donatella Vincelli, Claudia Cellini, Fortunato Morabito, Mauro Girotto, Mariella Grasso, Antonio Palumbo, Roman Hajek, Mario Boccadoro, Alessandra Larocca (abstract)
PS1294 – Pomalidomide, Cyclophosphamide And Dexamethasone In Case Of Suboptimal Response To Pomalidomide And Dexamethasone In Relapsed And Refractory Multiple Myeloma: Results Of The GMMG-PERSPECTIVE Trial
Katja Weisel, Hans Salwender, Christof Scheid, Manola Zago, Britta Besemer, Mathias Haenel, Jan Duerig, Markus Munder, Hans-Walter Lindemann, Anja Seckinger, Christina Kunz, Axel Benner, Dirk Hose, Anna Jauch, Lothar Kanz, Hartmut Goldschmidt (abstract)
PS1295 – SKY92 Risk Stratification At Relapse Provides Additional Prognostic Information For Standard-Risk Multiple Myeloma Patients
Rowan Kuiper, Erik H. van Beers, Martin H. van Vliet (abstract)
PS1296 – Carfilzomib, Cyclophosphamide, And Dexamethasone In Transplant Eligible Newly Diagnosed Multiple Myeloma: Preliminary Result Of SGHMM1 Trial, High-Risk Cohort (NCT02217163)
Yunxin Chen, Sathish Gopalakrishnan, Melissa Ooi, Nicholas Grigoropoulos, Yuh Shan Lee, Colin Phipps, Yeow Tee Goh, Wee Joo Chng, William Hwang, Chandramouli Nagarajan (abstract)
PS1297 – Weekly Carfilzomib, Lenalidomide, And Dexamethasone (KRd) In Relapsed Or Refractory Multiple Myeloma (RRMM): A Phase 1b Study
Noa Biran, David Siegel, Jesus G. Berdeja, Noopur Raje, R. Frank Cornell, Melissa Alsina, Tibor Kovacsovics, Belle Fang, Amy Kimball, Ola Landgren (abstract)
PS1298 – Extended 5-y Follow-Up Of Phase 3 ELOQUENT-2 Study: Elotuzumab Plus Lenalidomide / Dexamethasone vs Lenalidomide / Dexamethasone In Relapsed / Refractory Multiple Myeloma
Katja Weisel, Meletios A. Dimopoulos, Sagar Lonial, Darrell White, Philippe Moreau, Maria-Victoria Mateos, Jesus San Miguel, Kenneth Anderson, Ofer Shpilberg, Sebastian Grosicki, Ivan Spicka, Adam Walter-Croneck, Hila Magen, Andrew Belch, Donna Reece, Meral Beksac, Suresh G. Shelat, Sabeen Mekan, Oumar Sy, Anil K. Singhal, Paul G. Richardson (abstract)
PS1299 – Lenalidomide-Prednisone vs Lenalidomide Alone Maintenance In Newly Diagnosed Multiple Myeloma: Individual Patient Data Meta-Analysis Of 2 Randomized Phase III Trials.
Francesca Gay, Lorenzo De Paoli, Alessandra Larocca, Caterina Musolino, Mariella Genuardi, Vittorio Montefusco, Stefano Spada, Riccardo Centurioni, Enrico Aitini, Alessandra Malfitano, Giancarlo Latte, Giovanni De Sabbata, Federica De Santis, Norbert Pescosta, Pellegrino Musto, Giulia Benevolo, Tommasina Guglielmelli, Nicola Cascavilla, Francesca Patriarca, Concetta Conticello, Roman Hajek, Andrew Spencer, Mario Boccadoro (abstract)
PS1300 – A Global Treatment Standard In Multiple Myeloma (MM) Remains Elusive Despite Advances In Care Over 15 Years: First Results From INSIGHT MM, The Largest Global Prospective, Observational MM Study
Mario Boccadoro, Saad Z. Usmani, Ajai Chari, Robert Rifkin, Rafat Abonour, Jesus Berdeja, Gordon Cook, Caitlin Costello, Hartmut Goldschmidt, Roman Hajek, Vania Hungria, Hans C. Lee, Xavier Leleu, Jim Omel, Andrew Spencer, Michael A. Thompson, Jorge Vela-Ojeda, Jeffrey A. Zonder, Noemi Puig, Alfonzo Aguarón, Faith E. Davies, Brittany Demers, Kaili Ren, Shawn Yu, Tomas Skacel, Dawn Marie Stull, Evangelos Terpos (abstract)
PS1302 – Neutrophil Gelatinase-Associated Lipocalin As A Biomarker In Patients With Relapsed / Refractory Multiple Myeloma And Renal Impairment: Data From A Phase II Trial Of Pomalidomide Plus Dexamethasone
Katja Weisel, Meletios A. Dimopoulos, Frank Bridoux, Niels W.C.J. Van de Donk, Karthik Ramasamy, Elisabeth Kueenburg, Antonia Di Micco, Barbara Rosettani, Pamela Bacon, Pieter Sonneveld (abstract)
PS1303 – Real World Clinical Implications Of The Limitations Associated With The Revised International Staging System: Unselected Patients With Multiple Myeloma Treated With Novel Agents In Ageing Society
Yoshiaki Abe, Kentaro Narita, Hiroki Kobayashi, Akihiro Kitadate, Masami Takeuchi, Kosei Matsue (abstract)
PS1306 – Efficacy And Tolerability Of Daratumumab After Allogeneic Transplantation For Heavily Treated Multiple Myeloma.
Ana Pilar Gonzalez-Rodriguez, Lucia Lopez Corral, Arantxa Bermudez, Teresa Zudaire Ripa, Patricia Santos Diaz, Ana Julia Gonzalez-Huerta, Pilar Palomo, Maria-Victoria Mateos, Soledad Gonzalez-Muñiz (abstract)
PS1307 – Characteristics, Treatment Patterns, And Survival Outcomes Of Patients With Relapsed / Refractory Multiple Myeloma (RRMM) In North America And Europe: Findings From The PREAMBLE Study
Ravi Vij, Clara Chen, Catherine Davis, Hyang Kim, Brian Durie, Gordon Cook, Hartmut Goldschmidt (abstract)
PS1308 – Complete Response And Induction Treatment Does Not Affect Survival In Myeloma Patients Relapsing Within 18 Months Following Up-front HDM-ASCT. A Population-based Study From 1994 To 2015
Annette Vangsted, Stine Novrup Clemmensen, Kostas Dimoupolous, Ulf Christian Frølund, Carsten Helleberg, Niels Frost Andersen, Niels Abildgaard, Peter Gimsing, Henrik Gregersen, Tobias Wirenfeldt Klausen (abstract)
PS1309 – Overall Survival Of Patients Post-Transplant: Study Results From Two Phase 3 Trials ASPIRE And ENDEAVOR
Hartmut Goldschmidt, Maria-Victoria Mateos, David Siegel, Rafat Abonour, Heinz Ludwig, Mihaela Obreja, Karim Saad Iskander, Parameswaran Hari (abstract)
PS1310 – Durable Progression-Free Survival Benefit In Early Responders To Elotuzumab Plus Lenalidomide And Dexamethasone For Relapsed / Refractory Multiple Myeloma: Analysis Of 4-year Data From ELOQUENT-2
Christof Scheid, Christoph Röllig, Katja Weisel, Hans-Jürgen Salwender, Martin Gramatzki, Katrin Edmaier-Schröger, Oumar Sy, Hartmut Goldschmidt (abstract)
PS1311 – Serial Serum Free Light Chain Assay Can Reduce The Need For 24-hour Urine Protein Assessment For Response Assessment In Multiple Myeloma
Marcella Tschautscher, Vincent Rajkumar, Angela Dispenzieri, Martha Lacy, Morie Gertz, Francis Buadi, David Dingli, Lisa Hwa, Amie Fonder, Miriam Hobbs, Suzanne Hayman, Steven Zeldenrust, John Lust, Stephen Russell, Nelson Leung, Prashant Kapoor, Ronald Go, Yi Lin, Wilson Gonsalves, Taxiarchis Kourelis, Rahma Warsame, Robert Kyle, Shaji Kumar (abstract)
PS1312 – Novel Therapies Differentially Impact Polyclonal Immunoglobulin Recovery In Myeloma Patients: A Longitudinal Study
Mauricette Michallet, Colette Chapuis-Cellier, Christine Lombard, Mohamad Sobh, Thomas Dejoie, Helene Caillon, Michel Attal, Philippe Moreau, Herve Avet-Loiseau (abstract)
PS1313 – Real-World Outcomes In Transplant Ineligible NDMM Patients: Results From A Large UK Cohort
Faouzi Djebbari, Faye Sharpley, Samih Fourali, Grant Vallance, Susan McLain-Smith, Jaimal Kothari, Karthik Ramasamy (abstract)
PS1316 – Tandem Transplantation Overcomes Poor Prognosis In Newly Diagnosed Extramedullary Myeloma With High-Risk Cytogenetics: A Retrospective Study By The CMWP-EBMT
Nico Gagelmann, Diderik-Jan Eikema, Linda Koster, Denis Caillot, Pietro Pioltelli, Juan Bargay Lleonart, Peter Reményi, Didier Blaise, Nicolaas Schaap, Marek Trneny, Jakob Passweg, Rocio Parody Porras, Jean Yves Cahn, Maurizio Musso, Xavier Poiré, Guido Kobbe, Maija Itälä-Remes, Vincenzo Pavone, Loic Fouillard, Helene Schoemans, Dominique Bron, Anastasia Pouli, Wilfried Schroyens, Laurent Garderet, Nicolaus Kröger (abstract)
PS1317 – Venetoclax Monotherapy And Combined With Dexamethasone As Targeted Therapy For Relapsed / Refractory T(11;14) Multiple Myeloma
Jonathan Kaufman, Cristina Gasparetto, Joseph Mikhael, Philippe Moreau, Cyrille Touzeau, Ravi Vij, Thierry Facon, Brigitte Pegourie, Lofti Benboubker, Lawrence Boise, Wan Jen Hong, Yanwen Jiang, Stefanie Alzate, Martin Dunbar, John Pesko, Kevin Friese, Jeremy Ross, Paulo Maciag, Shaji Kumar (abstract)
PS1319 – Disease Assessment By PET-CT Plus Flow Cytometry In Multiple Myeloma Identifies Patients With Different Survival Outcomes
Rafael Alonso Fernández, María Teresa Cedena, Rafael Ríos, José María Moraleda, Valentín Cabañas, María José Moreno, Javier López-Jiménez, Alejandro Sanz, Fernando Martín, Antonio Valeri, Ana Jiménez, Adolfo Gómez-Grande, Juan José Lahuerta, Joaquín Martínez-López (abstract)
PS1321 – Ixazomib In Combination With Thalidomide And Dexamethasone For Induction And Ixazomib Maintenance Therapy In Patients With Relapsed / Refractory Multiple Myeloma
Heinz Ludwig, Wolfram Poenisch, Alexander Egle, Stefan Knop, Martin Schreder, Daniel Lechner, Roman Hajek, Eberhard Gunsililus, Michael Fridrik, Andreas Petzer, Katja Weisel, Dietger Niederwieser, Richard Greil, Niklas Zojer (abstract)
PS1322 – Selinexor Combined With Low Dose Bortezomib And Dexamethasone (SVd) Induces A High Response Rate In Patients With Relapsed Or Refractory Multiple Myeloma (MM)
Nizar Bahlis, Heather Sutherland, Darrell White, Michael Sebag, Suzanne Lentzsch, Rami Kotb, Chris Venner, Cristina Gasparetto, Gary Schiller, Richard LeBlanc, William Bensinger, Brea Lipe, Aldo Del Col, Michael Kauffman, Sharon Shacham, Jacqueline Jeha, Jean-Richard Saint-Martin, Jatin Shah, Christine Chen (abstract)
PS1323 – The Majority Of Newly Diagnosed Myeloma Patients Do Not Fulfil The Inclusion Criteria In Clinical Phase III Trials
Tobias Wirenfeldt Klausen, Henrik Gregersen, Niels Abildgaard, Niels Frost Andersen, Ulf Christian Frølund, Peter Gimsing, Carsten Helleberg, Katrine Fladeland Iversen, Per Trøllund Pedersen, Robert Schou Pedersen, Annette Juul Vangsted (abstract)
PS1324 – Comparison Of Lymphotrack® Miseq® Assays And Flow Cytometry For Clonality And Minimum Residual Disease Assessment In Multiple Myeloma
Ying Huang, Jeff Panganiban, Austin Jacobsen, Maggie Kaminsky, Kasey Hutt, Joshua Heilman, Fuensanta W. Martinez, Martin Blankfard, Tim Stenzel, Alejandro Medina, Cristina Jiménez, Ramón García-Sanz, Jeffrey E. Miller (abstract)
PS1326 – Sustained MRD Negativity At 12 Months Post-ASCT Predicts Outcomes For Myeloma Patients: A Real World Study.
Michael Austin, Charlotte Pawlyn, Helena Woods, Ricardo Morilla, Mike Potter, Mark Ethell, Radovan Saso, Martin Kaiser, Kevin Boyd (abstract)
PS1327 – Multiple Myeloma In Patients Under 40 Years Old: A Retrospective Analysis From The Intergoupe Francophone Du Myelome (IFM).
Alexis Caulier, Benoît Branco, Jean Galtier, Aurore Perrot, Anne-Victoire Michaud, Chantal Doyen, Brigitte Pegourie, Denis Caillot, Pascal Lenain, Sarah Ivanoff, Jean Fontan, Anne-Marie Stoppa, Salomon Manier, Laurent Garderet, Valentine Richez, Xavier Leleu, Jean-Pierre Marolleau, Hervé Avet-Loiseau, Bruno Royer (abstract)
PS1328 – Amplicon Next-Generation Sequencing (NGS) Of Rearranged Immunoglobulin (IG) Loci Is Advantageous For Clonal Marker Identification And Minimal Residual Disease (MRD) Detection In Multiple Myeloma (MM).
Michaela Kotrova, Franziska Appelt, Johanne Wangemann, Matthias Ritgen, Nikos Darzentas, Frederic Davi, Patricia Groenen, Monika Brüggemann, Stefan Knop, Thomas Stübig (abstract)
PS1329 – A Phase 1b Study Using The Combination Of Selinexor, Daratumumab, And Dexamethasome In Multiple Myeloma Patients Previously Exposed To Proteasome Inhibitors And Immunomodulatory Drugs
Cristina Gasparetto, Suzanne Lentzsch, Gary Schiller, William Bensinger, Nizar Bahlis, Heather Sutherland, Darrell White, Michael Sebag, Rami Kotb, Chris Venner, Richard LeBlanc, Christine Chen, Aldo Del Col, Michael Kauffman, Sharon Shacham, Jacqueline Jeha, Jean-Richard Saint-Martin, Jatin Shah, Joel Turner, Dan Sullivan, Brea Lipe (abstract)
PS1330 – A Real World Retrospective Analysis Of Extramedullary Disease From Balkan Myeloma Study Group And Barcelona University: Clinical Features And Outcome
Meral Beksac, Nick Kanellias, Laura Rosinol, Guldane Seval Cengiz, Gulsum Ozet, vesselina Goranova, Daniel Coriu, Jelena Bila, Hayri Ozsan, Lejla Ibricevic Balic, Arben Ivanaj, Efstathios Kastritis, Joan Blade, Meletios Dimopoulos (abstract)
PS1332 – Comparable Outcomes Using Propylene Glycol-Free Melphalan For Autologous Stem Cell Transplantation In Multiple Myeloma
Kevin Miller, Hasib Sidiqi, Morie Gertz, Francis Buadi, Suzanne Hayman, Martha Lacy, Angela Dispenzieri, David Dingli, Prashant Kapoor, Wilson Gonsalves, Taxiarchis Kourelis, William Hogan, Shaji Kumar (abstract)
PS1333 – Activity And Safety Of Daratumumab Monotherapy In Patients With Relapsed And Refractory Multiple Myeloma Requiring Dialysis: Preliminary Results Of A Spanish, Retrospective, Multicenter Trial
Maria-Jose Cejalvo, Mario Legarda, Eugenia Abella, Elena Cabezudo, Cristina Encinas, Ana García-Feria, Belén Íñigo, Jesús Martín, Paz Ribas, María-Ángeles Ruíz, Yolanda González, Javier Cornago, Ángel Ramírez, Pascual Fernández, Lucía Rubio, Javier de la Rubia (abstract)
PS1334 – Optimising Treatment For High-Risk Myeloma In A Stratified Multi-Centre Trial: Experience From MUKnine OPTIMUM Study
Vallari Shah, Samantha Hinsley, Amy Sherborne, Sidra Ellis, Amy Price, Jack Kendall, David Johnson, Roger Owen, Mark Drayson, Louise Flanagan, Debbie Sherratt, Walter Gregory, Graham Jackson, Guy Pratt, Gordon Cook, Sarah Brown, Matthew Jenner, Martin Kaiser (abstract)
PS1336 – Randomized Clinical Trial (RCT) Representativeness & Outcomes In Relapsed / Refractory Multiple Myeloma (RRMM) Real World (RW) Patients: Comparison Of ASPIRE, TOURMALINE-MM1, POLLUX, & ELOQUENT RCTs
Ajai Chari, Dorothy Romanus, Eileen Farrelly, Hui Huang, Marlo Blazer, Aditya Raju, Stephen Noga, Paul Richardson (abstract)
PS1337 – Pharmacokinetic Evaluation Of Test Dose Predictions Of High Dose Melphalan Exposure In Patients With Multiple Myeloma.
Judith Trotman, Peter Shaw, Campbell Tiley, Sundra Ramanathan, Andrew Grigg, Peter Presgrave, Elizabeth Newman, Jane Estell, Shir-Jing Ho, Stephen Larsen, Christa Nath (abstract)
PS1338 – A Phase Ii Study Of Selinexor (KPT-330) Combined With Bortezomib And Dexamethasone (SVd) For Induction And Consolidation For Patients With Progressive Or Refractory Multiple Myeloma: The Selvedex Trial
Annemiek Broijl, E.L. Asselbergs, M.C. Minnema, S. Lonergan, B. van der Holt, N. van de Donk, S. Zweegman, P. Sonneveld (abstract)
PS1339 – Long-Term Outcomes Of Allogeneic Hematopoietic Cell Transplantation In Patients With Newly Diagnosed Multiple Myeloma
Qaiser Bashir, Kamal Chamoun, Faisal H. Cheema, Betul Oran, Stefan Ciurea, Yago Nieto, Chitra Hosing, Uday R. Popat, Partow Kebriaei, Sairah Ahmed, Amanda Olson, Gheath Al-Atrash, Rohtesh Mehta, Robert Z. Orlowski, Elisabet E. Manasanch, Hans C. Lee, Krina Patel, E.J. Shpall, Richard E. Champlin, Muzaffar H. Qazilbash (abstract)
| Session | Non-Hodgkin Lymphoma Biology & Translational Research |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1386 – Enzyme-Free Digital Counting Of Endogenous Circular RNA Molecules In Formalin-Fixed Paraffin-Embedded Tissues From Patients With B-Cell Malignancies
Mette Dahl, Iben Daugaard, Maria Schertz Andersen, Thomas Birkballe Hansen, Kirsten Grønbæk, Jørgen Kjems, Lasse Sommer Kristensen (abstract)
| Session | Quality of Life, Palliative Care, Ethics and Health Economics |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1429 – Cost Comparison Of Treatment Strategies Following Initiation With Rd Versus VMP Plus Daratumumab In Newly Diagnosed Patients Ineligible For ASCT
Graham Jackson, Richard Dutton, Sujith Dhanasiri (abstract)
PS1440 – Clarithromycin Added To The VCD Regimen Causes Reduced Health-Related Quality Of Life In Multiple Myeloma Patients
Lene Kongsgaard Nielsen, Tobias Wirefeldt Klausen, Trung Do, Ida Bruun Kristensen, Ulf Christian Frølund, Niels Frost Andersen, Christen Lykkegaard Andersen, Annette Juul Vangsted, Niels Abildgaard, Henrik Gregersen (abstract)
PS1447 – Cost Per Median Month Of Progression‐Free Survival For Daratumumab Plus Bortezomib And Dexamethasone Compared With Carfilzomib Plus Dexamethasone In Relapsed / Refractory Multiple Myeloma
Eric Maiese, Christopher N. Graham, Emma Hawe, Jean‐Gabriel Le Moine (abstract)
| Session | Stem Cell Transplantation – Clinical |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1476 – Effects Of Post-Auto-HSCT MRI Bone Marrow Lesions On Progression-Free Survival In Patients With MM
Maxim Solovev, Larisa Mendeleeva, Galina Yatsyk, Natalia Lutsik, Maya Firsova, Valeri Savchenko (abstract)
PS1478 – After Allogeneic Hematopoietic Transplantation, A Composite Score Based On Plasmatic Levels Of IL-2 Receptor And TIM-3, Can Predict, At Day +18, TRM And Severe A-GVHD
Giuseppe Milone, Salvatore Leotta, Alessandra Cupri, Roberto Crocchiolo, Anna Elisa Marchese, Giuseppe Sapienza, andrea Spadaro, Giuseppe Avola, Luca Scalise, Giovanni Tripepi (abstract)
PS1481 – Changes In The Number Of Bone Marrow Lesions And Tumour Mass On MRI In Patients With MM Following Auto-HSCT
Maxim Solovev, Larisa Mendeleeva, Galina Yatsyk, Natalia Lutsik, Maya Firsova, Valeri Savchenko (abstract)
PS1495 – Elderly Patients With Multiple Myeloma: Long-Term Outcome Following Induction With Novel Drugs And Autologous Stem Cell Transplant
Swabirah Rassool, Lauren Foster, Yonghan Li, Saif Muhammad, Antonina Zhelyazkova, Chetan Patalappa, Simon Jowitt, Patrick Carrington, Hitesh Patel, Elizabeth Davies, Pippa Bulger, Muhammad Pervaiz, Sarah Burns, Camilo Humphrey, Naveeda Khaliq, Allameddine Allameddine, Sonya Ravenscroft, Hayley Greenfield, Jennifer Frazer, Wendy Ogden, Eleni Tholouli, Alberto Rocci (abstract)
| Session | Stem Cell Transplantation – Experimental |
| Type | Poster Presentations |
| Time | Saturday June 16, 5:30 PM - 7:00 PM |
| Location | Poster Area |
PS1507 – The Relationship Between Selective Pre-Transplantation Immune Parameters And Early Infections In Patients With Hematological Malignancies Undergoing ASCT – Preliminary Report
Joanna Mańko, Agnieszka Szymczyk, Agata Szymańska, Agnieszka Bojarska-Junak, Adam Walter-Croneck, Wojciech Legieć, Dariusz Jawniak, Jacek Roliński, Iwona Hus (abstract)
