EHA 2015 Multiple Myeloma Abstracts –
Poster Presentations June 13
There will be two sessions at the 2015 European Hematology Association (EHA) meeting where posters focused on multiple myeloma-related research will be displayed and visitors to the poster hall can speak with one of the poster's authors. The first session will be in the late afternoon on Friday, June 12. The second will be in the late afternoon on Saturday, June 13.
Listed below are titles and links to the abstracts for the myeloma-related posters that will be on display on Saturday, June 13. A separate list is available for posters to be presented on Friday, June 12. Both lists include transplantation-related posters with either direct or indirect relevance to multiple myeloma.
The Beacon also has a list of EHA 2015 of myeloma-related "e-posters," and a list of all myeloma-related oral presentations.
Links to PDF files containing posters will be added to entries in this list as those files are made available to The Beacon courtesy of the EHA presenters.
| Session | Multiple Myeloma - Biology 2 |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | (none listed) |
P636 - Effect Of IMiD Compounds On CD38 Expression On Multiple Myeloma Cells: MOR202, A Human CD38 Antibody In Combination With Pomalidomide
Rainer Boxhammer, Stefan Steidl, Jan Endell (abstract)
P637 - Centrosome Associated Genes Pattern For Risk Substratification In Multiple Myeloma
Fedor Kryukov, Pavel Nemec, Lenka Radova, Elena Kryukova, Zuzana Kufová, Lenka Sedlarikova, Sabina Sevcikova, Roman Hajek (abstract)
P638 - Bone Marrow Mesenchymal Stromal Cells From Healthy Donors Secrete Exosomes That Inhibit In Vivo Tumor Growth And Angiogenesis In Multiple Myeloma
Tomohiro Umezu, Satoshi Imanishi, Kenko Azuma, Seiichiro Yoshizawa, Kazuma Ohyashiki, Junko Ohyashiki (abstract)
P640 - Bortezomib-Resistance Of Bone Marrow Fibroblasts In Multiple Myeloma Is Closely Connected To Activation Of Autophagy As Survival Machinery
Lucia Di Marzo, Vanessa Desantis, Daniele Vergara, Kim De Veirman, Ivana Catacchio, Luigia Rao, Michele Maffia, Karin Vanderkerken, Angelo Vacca, Maria Antonia Frassanito (abstract)
P641 - Polymorphisms Within The Cereblon And Beta-Catenin Encoding Genes In Patients With Multiple Myeloma
Aleksandra Butrym, Justyna Rybka, Piotr Lacina, Katarzyna Gembura, Diana Frontkiewicz, Tomasz Wróbel, Katarzyna Bogunia-Kubik, Grzegorz Mazur (abstract)
P642 - A New Next Generation Sequencing Strategy To Evaluate Genetic Abnormalities In Multiple Myeloma
Cristina Jiménez, María Jara, Norma C Gutiérrez, Mª Eugenia Sarasquete, Noemí Puig, Mª Isabel Prieto-Conde, María García-Álvarez, Miguel Alcoceba, Elena Sebastián, Ana Balanzategui, Carmen Chillón, Rocío Corral, Luis A Marín, Mª Victoria Mateos, Jesús F San Miguel, Marcos González, Alberto Orfao, Ramón García-Sanz (abstract)
P643 - Human Myeloma Cell Engraftment In Next Generation Humanized Mice Expressing Human Interleukin 6
Tobias Silzle, Giovanni Pellegrini, David Kenkel, Sergio Cogliatti, Markus G. Manz, Christoph Driessen (abstract)
P644 - Overexpression Of Salivary-Type Amylase Reduces The Sensitivity To Bortezomib In Multiple Myeloma Cells
Shohei Mizuno, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Tomoko Narita, Masaki Ri, Mineaki Goto, Mayuko Gotou, Norikazu Tsunekawa, Masato Shikami, Shinsuke Iida, Yoshitaka Hosokawa, Hiroshi Miwa, Ryuzo Ueda, Nitta Masakazu, Akiyoshi Takami (abstract)
P639 - Antitumoral Activity Of Amiloride In Multiple Myeloma Through Apoptosis Induction, Regardless Of TP53 Mutational Status
Elizabeta Rojas, Irena Misiewicz-Krzeminska, Susana Hernández, Teresa Paíno, Luis Antonio Corchete, Isabel Isidro, María Victoria Mateos, Enrique Ocio, Norma C. Gutiérrez (abstract)
| Session | Multiple Myeloma - Clinical 3 |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | Sonja Zweegman |
P645 - A Systematic Literature Review And Network Meta-Analysis Of Treatments For Patients With Transplant-Ineligible Newly Diagnosed Multiple Myeloma
Weisel Katja, Chantal Doyen, Meletios A Dimopoulos, Adrian Yee, Martin Kropff, Juan José Lahuerta, Amber Martin, Karin Travers, Niels Abildgaard, Jin Lu, Jan Van Droogenbroeck, Catarina Geraldes, Mario Petrini, Laurent Voillat, Jean-Pierre Vilque, Eric Voog, Thierry Facon (abstract; poster [PDF] courtesy of Dr. Weisel)
P646 - Updated Results From A Multicenter, Open-Label, Dose-Escalation Phase 1b/2 Study Of Single-Agent Oprozomib (OPZ) In Patients (Pts) With Hematologic Malignancies, Including Multiple Myeloma (MM)
Ravi Vij, Michael Savona, David Siegel, Jonathan L. Kaufman, Ashraf Badros, Irene Ghobrial, Agne Paner, Sundar Jagannath, Andrzej Jakubowiak, Joseph Mikhael, Prashant Kapoor, Linda Neuman, Mihaela Obreja, Jesus Berdeja (abstract)
P647 - Multiple Myeloma Management: Practice Patterns Across Europe
Marc. S Raab, Michele Cavo, Michel Delforge, Christoph Driessen, Leah Fink, Alain Flinois, Sebastian Gonzalez-McQuire, Lionel Karlin, Maria-Victoria Mateos, Paul Schoen, Kwee Yong (abstract)
P648 - Multiple Infusions Of Autologous Activated And Expanded Natural Killer Cells: A New Therapeutic Option For Multiple Myeloma
Alejandra Leivas, Ruth M. Risueño, Antonio Pérez-Martínez, María Jesús Blanchard, Dario Campana, Juan José Lahuerta, Joaquín Martínez-López (abstract)
P649 - Multiple Myeloma Management: Outcomes In Real-World Practice
Kwee Yong, Michel Delforge, Christoph Driessen, Leah Fink, Alain Flinois, Sebastian Gonzalez-McQuire, Lionel Karlin, Maria-Victoria Mateos, Marc S. Raab, Paul Schoen, Michele Cavo (abstract)
P650 - European Post-Approval Safety Study (PASS) Of Relapsed/Refractory Multiple Myeloma (RRMM): VTE Incidence, Risk Factors, And Use Of Antithrombotic Prophylaxis In MM Patients Treated With Lenalidomide
Igor Blau, Miguel Hernandez, Christian Berthou, Eleni Tholouli, Elena Zamagni, Roman Hajek, Monique Minnema, Meletios A Dimopoulos, Barbara Gamberi, Pamela Bacon, Elisabeth Kueenburg, Barbara Rosettani, Nancy Brandenburg, Neil Minton, Gaetan Vanstraelen, Niels Andersen, Bjorn Andreasson (abstract)
P651 - Management Of Adverse Events In The STRATUS Trial, A Phase 3b Study Evaluating Safety And Efficacy Of Pomalidomide+Low-Dose Dexamethasone In Refractory Or Relapsed And Refractory Multiple Myeloma
Michele Cavo, Meletios A Dimopoulos, Philippe Moreau, Antonio Palumbo, Paola Corradini, Katja Weisel, Enrique Ocio, Chantal Doyen, Pekka Anttila, Reinier Raymakers, Jesus San Miguel, Xin Yu, Neil Milller, Jennifer Herring, Ana Slaughter, Teresa Peluso, Lars Sternas, Mohamed Zaki, Michel Delforge (abstract)
P652 - Single Center Experience With Early Versus Late Autologous Stem Cell Transplantation In Multiple Myeloma
Gergely Varga, Péter Reményi, Gábor Mikala, Marienn Réti, László Gopcsa, Árpád Bátai, Zoltán Csukly, Lilla Lengyel, Éva Torbágyi, Anikó Barta, János Fábián, Dóra Lévai, Gergely Szombath, Péter Farkas, Hajnalka Andrikovics, Attila Tordai, Tamás Masszi (abstract)
P653 - Oprozomib (OPZ) And Dexamethasone (Dex) In Patients (Pts) With Relapsed And/or Refractory Multiple Myeloma (RRMM): Updated Results From Dose Escalation In A Phase 1b/2, Multicenter, Open-Label Study
Parameswaran Hari, Kenneth H. Shain, Peter Voorhees, Nashat Gabrail, Muneer Abidi, Jeffrey Zonder, Ralph Boccia, Paul G. Richardson, Linda Neuman, Hansen Wong, Sandra Dixon, Claudia Paba Prada (abstract)
P654 - Prognostic Impact Of Immunophenotypic Response And Normalization Of Serum Free Light Chain Among Patients With Multiple Myeloma
Kota Fukumoto, Yasuhito Suehara, Manabu Fujisawa, Hiroki Sugihara, Masami Takeuchi, Kosei Matsue (abstract)
| Session | Multiple Myeloma - Clinical 4 |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | Pellegrino Musto |
P655 - A Prior Cancer Diagnosis Is Not A Risk Factor For The Developement Of Subsequent Cancers In Multiple Myeloma Patients
Gudbjörg Jónsdóttir, Sigrún H. Lund, Magnus Bjorkholm, Malin Hultcrantz, Ola Landgren, Sigurdur Y. Kristinsson (abstract)
P656 - Melphalan In Combination With Bortezomib And Dexamethasone (BMDex) Produces More Durable Responses Than Cyclophosphamide (CyBorD): A Matched Case-Control Study
Paolo Milani, Andrea Foli, Marco Basset, Giampaolo Merlini, Giovanni Palladini (abstract)
P657 - Evaluation Of Current Clinical Models For Risk Of Progression From Smoldering Multiple Myeloma To Multiple Myeloma In 287 Patients Followed In The Czech Republic
Vera Sandecka, Roman Hajek, Zdenek Adam, Ivan Spicka, Vlastimil Scudla, Evžen Gregora, Jakub Radocha, Lucie Brozova, Jaroslav Jarkovsky, Lucie Rihova, Aneta Mikulasova, David Starostka, Lenka Walterova, Dagmar Adamova, Petr Kessler, Martin Brejcha, Ivan Vonke, Jana Obernauerova, Kamila Valentova, Ludek Pour, Jiri Minarik, Jan Straub, Jaromir Gumulec, Vladimir Maisnar (abstract)
P658 - Venetoclax (ABT-199/GDC-0199) Monotherapy For Relapsed/refractory Multiple Myeloma: Phase I Safety And Efficacy
Shaji Kumar, Ravi Vij, Jonathan L Kaufman, Joseph Mikhael, Thierry Facon, Philippe Moreau, Martine Amiot, Stefanie Alzate, Lura Morris, Jeremy Ross, Martin Dunbar, Ming Zhu, Suresh Agarwal, Joel Leverson, Sari Enschede, Rod Humerickhouse, Cyrille Touzeau (abstract)
P660 - Post Relapse Outcomes In Young Patients With Multiple Myeloma In The Era Of Novel Agents
Nishanth Vallumsetla, Shaji Kumar, Morie Gertz, Utkarsh Painuly, Angela Dispenzieri, Martha Lacy, Francis Buadi, Ronald Go, David Dingli, Nelson Leung, Robert Kyle, Vincent Rajkumar, Prashant Kapoor (abstract)
P661 - SKY92 GEP, iFISH And ISS Comparisons For Risk Stratification In Multiple Myeloma
Erik van Beers, Martin van Vliet, Leonie de Best, Walter Gregory, Gareth Morgan, Hartmut Goldschmidt, Rowan Kuiper, Mark van Duin, Annemiek Broijl, Pieter Sonneveld (abstract)
P662 - Markers Of Disease Evolution In Smoldering Multiple Myeloma (SMM)
Eftychia Nikolaou, Tatiana Tzenou, Aikaterini Bitsani, Vasiliki Bartzis, Sotiria Kotsanti, Efstathios Koulieris, Maria Dimou, Dimitrios Maltezas, Theodoros Iliakis, Panayiotis Panayiotidis, Marie-Christine Kyrtsonis (abstract)
P663 - Efficiency And Toxicity Of Cyclophosphamide Based Stem Cell Mobilization In Relapsed Multiple Myeloma Patients: Observations From The Ongoing Phase III Trial ReLApsE
MA Baertsch, P Wuchter, J Schlenzka, K Weisel, R Noppeney, H Martin, HW Lindemann, M Haenel, A Nogai, C Scheid, H Salwender, R Fenk, U Graeven, P Reimer, M Schmidt-Hieber, M Goerner, IGH Schmidt-Wolf, S Klein, AD Ho, H Goldschmidt (abstract)
P664 - Heavy Light Chain Ratio Normalization Allows Identification Of Electrophoretic Non-Complete Response Patients With Improved Outcomes: A Long Term Follow Up Update For BMT CTN 0102 Correlative Study.
Anita D'Souza, Marcelo Pasquini, Brent Logan, Sergio Giralt, Amrita Krishnan, Joseph Antin, Alan Howard, Mary Horowitz, Stacey Goodman, Ginna Laport, Muzaffar Qazilbash, Adam Mendizabal, Firoozeh Sahebi, Daniel Weisdorf, David Vesole, Edward Stadtmauer, David Maloney, Parameswaran Hari (abstract)
| Session | Stem Cell Transplantation - Experimental |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | Andrzej Lange |
P693 - Endothelial Cell Microparticles-Delivery miR-155 Promotes The Development Of aGVHD By Modulating T Cells
Qiuling Wu, Haorui Shen, Mei Hong, Linghui Xia (abstract)
P696 - Simple, Efficient, And Safe Processing Of Frozen-Thawed Umbilical Cord-Derived Mesenchymal Stromal Cells Applied For The Treatment Of GVHD
Tokiko Nagamura-Inoue, Yuka Mori, Atsuko Takahashi, Takahisa Shimazu, Hajime Tsunoda, Arinobu Tojo (abstract)
P697 - The Impact Of NFAT Inhibition On Neutrophil Effector Functions In Patients After Allogeneic Hematopoietic Stem Cell Transplantation
Katharina Plein, Daniel Teschner, Christian Michel, Pamela Stein, Eva Maria Wagner, Matthias Theobald, Hansjörg Schild, Markus Radsak (abstract)
P698 - Inhibition Of Transforming Growth Factor Βeta-Activated Kinase 1 Suppresses Alloreactivity And Improves Survival In A Murine Marrow Transplantation Model
Ayako Kobayashi, Shinichi Kobayashi, Yukiko Osawa, Takaaki Maekawa, Takeshi Yamamura, Junichi Watanabe, Kosuke Miyai, Hitoshi Tsuda, Ken Sato, Fumihiko Kimura (abstract)
P699 - Distinct Exosomal miRNA Expression Of Late Onset Graft-Versus-Host Disease In Allogeneic Hematopoietic Stem Cell Transplantation
Seiichiro Yoshizawa, Tomohiro Umezu, Yuu Saitoh, Moritaka Gotoh, Daigo Akahane, Chiaki Kobayashi, Junko H Ohyashiki, Kazuma Ohyashiki (abstract)
P700 - Femur Target Cell Transplantation Can Be Achieved By Magnetism-Induced Cell Target Transplantation (MagIC-TT) In Murine Transplantation Model
Hao Huang, Yanyan Ye, Qianli Jiang, Qiusui Mai, Changxin Yin, Yuncong Lu, Jianpeng Wang, Li Liu, Yongjun Zhou, Xiaowei Sun, Minchun Zhang, Jieli Qin, Lezhong Yuan, Yifang Yuan, Qiuxia Zhang, Jing Sun, Qifa Liu (abstract)
| Session | Stem Cell Transplantation - Clinical 2 |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | A Urbano-Ispizua |
P702 - Complement-binding Donor-Specific Anti-HLA Antibodies And Risk Of Primary Graft Failure In Hematopoietic Stem Cell Transplantation
Stefan Ciurea, Piyanuch Kongtim, Uday Popat, Fleur Aung, Richard Champlin, Kai Cao (abstract)
P705 - Combination Therapy With Inolimomab And Etanercept For Severe Steroid-Refractory Acute Graft-Versus-Host Disease
Lenneke Van Groningen, Aleida Liefferink, Anton de Haan, Nicolaas Schaap, Peter Donnelly, Nicole Blijlevens, Walter van der Velden (abstract)
P707 - Donor Chimerism As Marker Of Relapses After Bone Marrow Transplantation
Ildar Barkhatov, Alexei Evdokimov, Alena Shakirova, Vera Teplyashina, Sergey Bondarenko, Alexei Chukhlovin, Ludmila Zubarovskaya, Boris Afanasyev (abstract)
P710 - Risk Factors For Transplantation-associated Thrombotic Microangiopathy And Outcome Of Patients, Following Allogeneic Hematopoietic Stem Cell Transplantation
Katalin Balassa, Hajnalka Andrikovics, Peter Remenyi, Arpad Batai, Andras Bors, Katalin Piroska Kiss, Lilla Lengyel, Eva Torbagyi, Aniko Barta, Aniko Szilvasi, Katalin Rajczy, Dora Inotai, Attila Tordai, Tamas Masszi (abstract)
P712 - Factors Determining The Effectiveness Of Acute Graft Versus Host Disease Prophylaxis After Allogeneic Bone Marrow Transplantation With Multipotent Mesenchymal Stromal Cells
Nataliya Petinati, Irina Shipounova, Alexey Bigildeev, Natalia Sats, Nina Drize, Larisa Kuzmina, Elena Parovichnikova, Valery Savchenko (abstract)
| Session | Stem Cell Transplantation - Clinical 4 |
| Type | Poster Presentations |
| Time | Saturday June 13, 5:15 PM - 6:45 PM |
| Location | Poster Area (Hall C) |
| Chair | C Castilla |
P714 - Alpha / Beta T-cell Depleted Allogeneic Stem Cell Transplantation From Matched Related And Unrelated Donor Grafts In Patients With High Risk Hematological Malignancies
Moniek de De Witte, Gerjan Fleurke, Lotte van de Wagen, Ineke Slaper, Jurgen Kuball (abstract)
P717 - Engraftment Syndrome (ES) After Allogeneic Stem Cell Transplantation: A High Incidence In Haploidentical Setting
Yao Chen, Lan-Ping Xu, Kai-Yan Liu, Huan Chen, Yu-Hong Chen, Xiao-Hui Zhang, Yu Wang, Xiao-Jun Huang (abstract)
P719 - Influence Of CYP3A5 Gene Polymorphisms On Pharmacokinetics Of Tacrolimus Modified-Release Once-Daily After Hematopoietic Stem Cell Transplantation
Takaya Yamashita, Naohito Fujishima, Masatomo Miura, Takenori Niioka, Maiko Abumiya, Kazuaki Teshima, Kumi Ubukawa, Miho Nara, Masumi Fujishima, Yoshihiro Kameoka, Makoto Hirokawa, Naoto Takahashi (abstract)
P722 - Incidence, Risk Factors, And Outcome Of Early Hemostatic Complications In Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Multicenter Study Of 551 Patients
Yue Han, Wei Han, Luping Hu, Yaqiong Tang, Jie Wang, Huiying Qiu, Aining Sun, Changgeng Ruan, Depei Wu (abstract)