Dexamethasone, which is also sold under the brand name Decadron, is a powerful corticosteroid. Multiple myeloma patients can use dexamethasone by itself or in combination with a number of other anti-myeloma agents.

Dexamethasone (dex) works so well with novel therapy agents like Velcade (bortezomib) and Revlimid (lenalidomide), the manufacturer should come up with an advertising slogan like: “Multiple myeloma drugs work better with dex!”

Dex can reduce inflammation and reduce bone pain. Most importantly, it contains powerful, unknown …

In this week’s column I would like to share some of my observations and thoughts about where I think the treatment of multiple myeloma is heading.

First, the good news: More drugs are being developed now for myeloma than for any other cancer. And, for the most part, they are working! These drugs—pomalidomide, carfilzomib, perifosine, Zolinza (vorinostat), etc.—most often work best when combined with other approved novel therapy agents thalidomide (Thalomid), Revlimid (lenalidomide), and/or …

I want to thank all of the readers who took the time to pass along helpful tips for staying positive last week.

Keeping a positive attitude in the face of a cancer diagnosis and treatment isn’t easy. But a positive attitude is the cornerstone of improving any patient’s quality of life during treatment.

Enough with the general, philosophical stuff! Here are a few practical suggestions to help multiple myeloma patients and caregivers make it through their day:

Keep moving. Go …

Last week, I promised to share a few tips that some of my multiple myeloma friends use to stay positive.

Staying positive does not cure cancer—and it probably doesn’t help extend a patient’s life. Surprised? Don’t be. There are a number of studies which prove this to be the case, including a large, 1,000 patient study, published in 2007 in the American Cancer Society’s journal Cancer.

A reader once commented on one of my blogs, “Pushing the idea that …

Before I get started, a word of warning: This column isn’t going to be a collection of tips on “how to handle dexamethasone side-effects.” I would be glad to write about that sometime in the future.

No, this column is about how patients can and should philosophically deal with side-effects caused by their multiple myeloma therapy. Philosophically? “What does philosophy have to do with my peripheral neuropathy or inconvenient constipation?” you might ask.

Here’s the thing. I don’t want to …

Last week, I spoke briefly with Greg Geissman, a public relations contact at Celgene, about the projected timeline for a new Phase 3 pomalidomide  research study in multiple myeloma.

As Greg finished describing the timeline, my mind wondered. I began to think about how different people view time.

Greg explained that it will take six months or more to find enough qualifying patients willing to participate in the study. The study itself will then take several years to complete. …

Late last year, my mother-in-law, Marie, lost her long battle with colon cancer. A few months before she died, I remember visiting her in the nursing home on a particularly bad day in September.

Marie was in pain—a lot of pain. I checked with the nurses station. The evening nurse was sympathetic, but unable or unwilling to help.

Fast forward one week. Marie seemed to be doing better. But not before my wife, Pattie, and I "rattled a few …