A recent study in mice reveals that treatment using an antibody, called anti-CD137, enhances the immune system’s response against multiple myeloma tumors. The positive results of this preclinical study suggest that anti-CD137, a type of cancer immunotherapy, may be suitable for use in human multiple myeloma patients.
Cancer immunotherapy helps the immune system fight cancer. It has emerged in recent years as an alternative to high-dose chemotherapy and stem cell transplantation treatments.
Following a dose of chemotherapy, …
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Overview
Multiple myeloma, like most medical conditions, manifests itself slightly differently in each patient. Because multiple myeloma can affect many organs, several possible symptoms exist, and they vary greatly. No sign or symptom is a direct indicator of multiple myeloma. Any symptom may be due to other causes, and multiple myeloma may initially cause no symptoms at all.
Multiple myeloma occurs when cancerous myeloma cells collect in many bones, unlike a plasmacytoma, which only involves a solid tumor in one …
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Bortezomib (originally PS-341 and marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease. [...]Read the full story »
