Boris Simkovich's Archive

Boris is the Founder and Publisher of The Myeloma Beacon. Prior to founding The Beacon, Boris worked in Internet publishing, management consulting, and academia. Boris was born and raised in Pennsylvania, but his studies and work took him afield for many years before he returned to the fold 15 years ago. He has a B.S. in nuclear engineering from Penn State and a Ph.D. in economics from Harvard. Boris is a fan of good television, and he is baffled by the many challenges involved in domesticating the two feral cats he recently rescued.

Boris Simkovich has written 74 article(s) .

[ by and | May 27, 2016 5:44 pm | One Comment ]
Myeloma Morning: Early Relapse And Survival, And Ninlaro & Kyprolis In Europe

How has your week been, myeloma world?

Summer definitely is here at Myeloma Morning Headquarters. We had temper­a­tures yesterday and today that rival those normally seen in early August.

We're not exactly sure how we feel about this devel­op­ment.

As for myeloma-related news, we have a lot of ground to cover.

We have one new myeloma research study that we summarize at length. It's about a difficult subject, namely, the impact of early relapse on the over­all survival of multiple …

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[ by and | May 23, 2016 11:41 am | One Comment ]
Myeloma Morning: Transplants In Patients With Kidney Impairment And In Older Patients

Good morning, myeloma world.

We hope you had a pleasant weekend and that your new week is off to a good start.

The big news today is that Darzalex (daratumumab) has been approved in Europe as a new treatment for multiple myeloma. We will be pub­lish­ing a separate news article on the approval, which was announced a few hours ago. In the mean­time, you can find information about the approval in this press release from Genmab, the …

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[ by and | May 20, 2016 12:22 pm | Comments Off ]
Myeloma Morning: Important New Transplantation And Darzalex Trial Results, And More

Good morning, myeloma world.

Since the last edition of Myeloma Morning, abstracts for two im­por­tant upcoming medical meetings have been made public: the American Society of Clinical Oncology (ASCO) annual meeting, which will take place June 3 through June 7 in Chicago, and the European Hematology Association (EHA) annual congress, which is scheduled for June 9 through June 12 in Copenhagen, Denmark.

The publication of the abstracts and the meetings themselves mean that there is going to be a lot …

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[ by and | May 17, 2016 5:35 pm | Comments Off ]
Myeloma Morning: Survival & Age, Once-Weekly Kyprolis, And Revlimid & Neutropenia

Hello, myeloma world.

We hope your week has gotten off to a great start.

We're looking forward to reviewing three new myeloma-related research studies with you today.

The first study we summarize in today's report focuses on the survival of older blood cancer patients, including (of course) older multiple myeloma patients.

The second study presents the results of the CHAMPION-1 clinical trial, which tested once weekly Kyprolis in com­bi­na­tion with dexa­meth­a­sone in re­lapsed multiple myeloma patients.

The final study we …

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[ by and | May 14, 2016 2:14 am | One Comment ]
Myeloma Morning: A T(11;14) Deep Dive, And Subcutaneous Fat & Overall Survival

It's good to see you again, myeloma world.

We got tied up the past couple days with, among other things, coverage of the Empliciti approval in Europe. But we're glad to be back and we have two new research studies that we'd like to discuss with you.

First, we take a look at an Israeli study that does a deep dive into the t(11;14) chro­mosomal abnormality in newly diagnosed multiple myeloma patients. The focus of this particular deep dive …

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[ by and | May 10, 2016 8:09 am | 8 Comments ]
Myeloma Morning: Velcade And Eyelid Inflammations, Imaging, And Race & Weight

How has your week started, myeloma world?

We hope it's going well so far.

We once again have a rather long list of new myeloma research we'd like to discuss with you. We sus­pect most of our readers will find at least one or two studies in the report to be of particular interest.

We begin today's report with a discussion of a somewhat rare eye-related side effect of Velcade (bor­tez­o­mib) and a possible way to control the …

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[ by | May 6, 2016 4:47 pm | One Comment ]
Myeloma Morning: Darzalex & YM155, The Sendai Virus, And Argonaute 2

Hello, myeloma world. How has your Friday been so far?

We have an eclectic mix of five new myeloma-related research studies that we'd like to discuss with you today.

Three of the studies involve laboratory (preclinical) research, which is the sort of research we often leave to discuss later in these reports. But all three of the laboratory studies we cover today address interesting topics, so we will be looking at them first.

The first laboratory study concerns

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