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Stem cell harvest failed - should I stress?

by ethomas on Fri Jan 23, 2015 12:09 am

I have been going to City of Hope here in Southern California for collection the last 2 days (January 21 and 22). With the Neupogen and Mozobil shots since Monday, I harvested around 1 million cells, which is way less than the 2.5 that I need for transplant. I am really bummed with all the side effects of these meds.

My doctor told me I should come back in 2 or 3 months, go on Cytoxan (cyclophosphamide), and then harvest and do the transplant right after that. In the meantime, she wants me to stay on Revlimid.

Any encouraging words? Should I stress?

ethomas
Name: Emmanouel Thomas AKA Amo
Who do you know with myeloma?: Yes
When were you/they diagnosed?: August 14, 2014
Age at diagnosis: 65

Re: Stem cell harvest failed - should I stress?

by Sharon01 on Fri Jan 23, 2015 5:27 am

Hi there,

I will be interested in the answers from those further along the road than you and I.

I have my collection booked for next Wednesday, Thursday, and Friday, but I have been on 2 daily shots of Neupogen since Wednesday -- so for a full week by collection day.

How long were you on the injections for?

Cheers,
Sharon

Sharon01
Name: Sharon
Who do you know with myeloma?: Self
When were you/they diagnosed?: September 2014
Age at diagnosis: 48

Re: Stem cell harvest failed - should I stress?

by CindyBrown on Fri Jan 23, 2015 11:15 am

You may want to search my earlier post "Stem cell collection failed" (December 25, 2014).

I only got 2.4 million cells in December after conditioning with VTD-PACE and two daily doses of 600 Neupogen. I was very discouraged. My team had me wait until 30 days after the chemo regimen stopped, and I did two 12-hour infusions of etoposide followed by daily Neupogen. After 8 days, I had excruciating bone pain, and I collected on day 11 (I got blood and plasma on day 10 in prep for collection).

I got 21.52 million cells in a single collection. I have had a lot of chemo and extensive radiation due to a large plasmacytoma in my sacrum.

Don't give up hope! I will transplant on February 9.

CindyBrown
Name: Cindy Brown
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 4/26/14
Age at diagnosis: 48

Re: Stem cell harvest failed - should I stress?

by Steve on Fri Jan 23, 2015 1:24 pm

Hey EThomas,

I would point out that there is some disagreement among multiple myeloma experts as to whether Revlimid can significantly inhibit the collection of stem cells.

There are a number of articles here at The Myeloma Beacon that discuss that issue in some detail if you care to do a search or two to educate yourself.

Best,

S.

Steve
Name: Steve
Who do you know with myeloma?: myself
When were you/they diagnosed?: December 2009
Age at diagnosis: 55


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